Evaluating Non-Motor Fluctuations in Parkinson’s Disease Using a Visual Analogue Scale
Objective: To further understand non-motor fluctuations (NMF) and their relationship to other symptoms of Parkinson’s disease (PD) in a deep brain stimulation (DBS) population. Background:…Levodopa effect and motor function in late stage Parkinson’s disease
Objective: To assess responsiveness to Levodopa (L-dopa) in patients with late stage Parkinson’s disease (PD). Moreover, to investigate if the L-dopa effect is stable or…Translation and validation of the Filipino version of the wearing-off questionnaire-19 (F-WOQ-19)
Objective: This study aims to translate the Wearing-Off Questionnaire (WOQ) 19 into Filipino (F-WOQ-19) and validate the translated questionnaire. Background: Parkinson’s disease (PD) is a…Early morning OFF problems are common in PD patients attending a routine clinical appointment
Objective: To characterize early morning OFF problems in consecutive PD patients attending a routine clinical appointment. Background: In PD patients with motor fluctuations, total daily…The FDA is listening: Integrating the voice of the patient in drug development for Parkinson’s and Huntington’s diseases.
Objective: To present highlights from the Patient-Focused Drug Development (PFDD) meetings held at FDA for Parkinson’s disease (PD) and Huntington’s disease (HD) to raise awareness…Motor effects and safety of IPX203, an investigational extended-release formulation of carbidopa-levodopa, in advanced Parkinson’s disease: A single-dose study
Objective: Evaluate the efficacy and safety of IPX203 vs. immediate-release (IR) carbidopa-levodopa (CD-LD) and vs. extended-release (ER) CD-LD (IPX066, RYTARY®) in patients with advanced Parkinson’s…Impact and communication of OFF periods in Parkinson disease
Objective: To review existing literature on the impact and communication of OFF periods for patients with Parkinson disease (PwP) and carepartners. Background: Studies show associations…Post-hoc analyses of the recommended starting dose for Rytary based on “off” time
Objective: To determine whether correcting for “off” time duration improves the selection of the final LD dose when converting to extended-release carbidopa-levodopa capsules (ER CD-LD,…The Personal Kinetigraph Fluctuator Score Identifies Motor Fluctuations in Parkinson’s disease
Objective: To evaluate the Personal Kinetigraph (PKG) fluctuator score (FS) in detecting motor fluctuations in Parkinson's disease (PD) patients. Background: Fluctuations of response to levodopa,…Clinical feasibility of a wearable, conformable, sensor patch to monitor motor symptoms in Parkinson’s disease
Objective: 2-part pilot study to evaluate feasibility of a wearable sensor, the prototype NIMBLE system sensor patch, to assess motor symptoms in Parkinson’s disease (PD) patients.…
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