Evaluating the clinical utility of the Parkinson’s KinetiGraph (PKG™) in the remote management of Parkinson’s disease
Objective: To evaluate the clinical utility of the Parkinson’s Kinetigraph (PKG™) in the remote management of Parkinson’s disease (PD) in terms of assistance with therapeutic…Determinants of absence of dyskinesia in Parkinson’s disease patients with treatment beyond 10 years
Objective: This study aims to explore the determinants for absence of dyskinesia in patients with Parkinson’s disease (PD) based on a large cohort of Chinese…Putaminal dopamine depletion in de novo Parkinson’s disease predicts future development of wearing-off
Objective: The present study aimed to investigate whether the level of presynaptic dopamine neuronal loss predicts future development of wearing-off in de novo Parkinson’s disease.…Absence of wearing-off in Parkinson’s disease patients with treatment beyond 10 years
Objective: This study aims to explore the determinants for absence of wearing-off in patients with Parkinson’s disease (PD) based on a large cohort of Chinese…Cardiac sympathetic denervation can predict the wearing-off phenomenon in patients with Parkinson’s disease
Objective: To investigate whether cardiac sympathetic denervation increases the risk of the early wearing-off phenomenon in Parkinson's disease (PD). Background: Recent studies have suggested that…Efficacy of CVT-301 (levodopa inhalation powder) for treatment of OFF periods in Parkinson’s disease
Objective: Post-hoc analysis of subjects with Parkinson’s disease (PD) achieving > 30% reduction in UPDRS motor score (UPDRSIII) from pre- to post-dose over the first…Safinamide and Rasagiline effect on motor fluctuation, sleep quality and daytime sleepiness in Parkinson’s Disease: A validated questionnaires study
Objective: This is an observational study aimed at evaluating the effect of Safinamide and Rasagiline on motor fluctuations, subjective sleep and daytime sleepiness in Parkinson’s…Safety of sublingual apomorphine film (APL-130277) for the treatment of OFF episodes in patients with Parkinson’s disease: Results from a Phase 3 double-blind, placebo-controlled trial
Objective: To evaluate the safety of APL-130277 (APL) in the double-blind, placebo-controlled trial Titration Phase (TP) and Maintenance Phase (MP). Background: OFF episodes are a…Motor and non-motor symptoms of a 7.5-year prospective study of patients with Parkinson’s disease
Objective: Previously, we retrospectively reported the prevalence and risks of motor and non-motor symptoms of a large number of patients (1453) with Parkinson’s disease (PD)…Individualization of levodopa treatment using a microtablet dispenser and ambulatory accelerometry
Objective: This four-week open-label observational study describes the effect of introducing a microtablet dose dispenser and adjusting doses based on objective free-living motor symptom monitoring…
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