Clinical feasibility of a wearable, conformable, sensor patch to monitor motor symptoms in Parkinson’s disease
Objective: 2-part pilot study to evaluate feasibility of a wearable sensor, the prototype NIMBLE system sensor patch, to assess motor symptoms in Parkinson’s disease (PD) patients.…Evaluating the Clinical Efficacy of the Personal KinetiGraph Movement Recording System
Objective: To examine the clinical efficacy of the Personal KinetiGraph (PKG) movement recording in identifying patients with Parkinson’s disease (PD) requiring treatment for motor symptoms.…Improved Detection of Gait Abnormalities in Parkinson’s disease using an IMU Sensor-based System
Objective: To develop an automated system that uses a limited set of IMU sensors to improve the detection of gait abnormalities in Parkinson’s disease during…Personal KinetiGraph (PKG) for Parkinson’s Disease: Experience at a Tertiary Care Center
Objective: To assess objective measurements by Personal KinetiGraph (PKG) in Parkinson’s disease (PD) patients and compare them to self-reported symptoms. Background: Personal Kinetigraph (PKG)…Objective decrement in Parkinson’s disease – A new parameter for the BRAIN tap test
Objective: To evaluate a new parameter – Bradykinesia Index (BI) as an new objective measure within the BRAIN (BRadykinesia Akinesia INcoordination) tap test. Background: The…Safety, pharmacokinetics, and efficacy of levodopa prodrug ONO-2160/CD: A study in patients with Parkinson’s disease
Objective: The objective of this study was to evaluate the safety, pharmacokinetic profile, and efficacy of ONO-2160/carbidopa (CD) and to compare them with an immediate-release…Validation of an electronic motor diary for patients with Parkinson’s disease
Objective: To determine the reliability and compliance to electronic motor diary in patients with PD. Background: Complexity of motor complications in Parkinson's disease (PD) makes…Pharmacokinetic profile of ONO-2160/CD (levodopa prodrug/carbidopa) in animal and human
Objective: The objective of this study was to characterize pharmacokinetic profile of levodopa prodrug ONO-2160 in animal and human. Background: Motor complications of Parkinson's disease…Construction of a levodopa-response index from wearable sensors for quantifying Parkinson’s disease motor functions: Preliminary results
Objective: The goal of the study is to investigate whether wrist worn motion sensors are feasible tools to measure motor functions in Parkinson's disease (PD).…Switching double-blind opicapone, entacapone or placebo to open-label opicapone: Efficacy results of the 1-year extension of study BIPARK I
Objective: Evaluate the efficacy of opicapone (OPC) in Parkinson's disease (PD) patients with motor fluctuations enrolled in the 1-year extension of study BIPARK I. Background:…
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