Characterising early morning akinesia and off (EMO) using Parkinson’s kinetigraph: analysis from a two centre national database in Parkinson’s disease .
Objective: Could wearable sensors such as Parkinson’s kinetograph (PKG) may provide valuable overnight data to detect EMO to augment care in clinic. Background: Early morning…Combining Carbidopa/levodopa Extended-release Capsules and Immediate-release Tablets – Crucial Factors of This Economical Prescription
Objective: We introduced a new way of prescribing carbidopa/levodopa extended-release (ER) capsule – combining use of immediate-release (IR) tablets. This retrospective clinical study was designed…Real-world Programming and Sensing from Adaptive Deep Brain Stimulation for Parkinson’s Disease in Japan
Objective: To characterize programming configurations and local field potentials (LFP) control parameters in a multicenter, real-world cohort of patients receiving deep brain stimulation (DBS) for…Smartwatch-Based Screening to Identify Candidates for Deep Brain Stimulation in Parkinson’s Disease
Objective: To use smartwatches to identify candidates for deep brain stimulation (DBS). Background: DBS can meaningfully lessen Parkinson's disease (PD) motor symptoms and improve quality…Measuring Motor Improvement with a Wearable Device in a Parkinson Disease Patient undergoing Subcutaneous Levodopa Carbidopa Infusion
Objective: To assess the feasibility of a wearable device for objective quantification of motor improvement in Parkinson's Disease (PD) patients undergoing a therapy from oral…Clinical Profile of Motor Complications in Parkinson’s Disease Patients at A National Tertiary Hospital In Indonesia
Objective: To analyse factors associated with motor complications in Parkinson's disease at a national tertiary referral hospital in Indonesia. Background: As Parkinson's disease progresses, levodopa…Efficacy of levodopa/carbidopa/entacapone replacement of levodopa/dopa decarboxylase inhibitors in treatment of Chinese Parkinson’s disease patients with wearing-off: a multicenter, randomized controlled, open label study
Objective: This study aimed to investigate the efficacy and safety comparison between LCE and Pramexol in Chinese PD patients with the wearing-off phenomenon. Background: Wearing…Measuring the heterogeneity of disease progression in Parkinson’s disease with multimodal clinical milestones over 10 years in the DeNoPa cohort
Objective: To provide a reference of individual Parkinson’s disease (PD) progression by assessing multimodal milestones over 10 years (y) in patients of the DeNoPa cohort.…COPS: Continuous Observation of Parkinsonian Symptoms – A prospective data acquisition study using wearable accelerometery
Objective: To investigate the continuous and objective assessment of motor symptom severity in Parkinson’s Disease (PD) in everyday life. Background: Treatment adjustments in PD patients…Motor function in Parkinson´s disease during 16h treatment with intravenously (DIZ101), subcutaneously (DIZ102), or intestinally (LCIG) infused levodopa
Objective: To compare the effect of intravenous (DIZ101) and subcutaneous (DIZ102) continuous 16h infusion of a continuously buffered acidic levodopa/carbidopa solution with levodopa/carbidopa intestinal gel…
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