MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Vesicle monamine transporter(VMAT2)"

  • 2025 International Congress

    Valbenazine Improves Chorea Across Multiple Body Regions in Adults With Huntington’s Disease

    E. Furr Stimming, E. Kayson, R. Mehanna, J. Goldstein, S. Hinton, O. Klepitskaya, H. Zhang, D. Haubenberger (Houston, USA)

    Objective: To evaluate valbenazine’s effects on chorea across body regions in adults with Huntington’s disease (HD) using data from KINECT®-HD (NCT04102579). Background: Once-daily valbenazine is…
  • 2025 International Congress

    Decreased Disease Burden in Motor-Related HD-HI Domains Among Adults With Huntington’s Disease Treated With Valbenazine

    E. Furr Stimming, H. Zhang, O. Klepitskaya, D. Haubenberger, S. Hinton, C. Heatwole (Houston, USA)

    Objective: To evaluate the effects of valbenazine (VBZ) on mobility, abnormal movements, and hand/arm function as assessed using the Huntington’s Disease Health Index (HD-HI). Background:…
  • 2025 International Congress

    Long-Term Safety and Efficacy of Valbenazine for Treating Huntington’s Disease Chorea

    E. Furr Stimming, E. Kayson, S. Karpuram, J. Goldstein, S. Hinton, O. Klepitskaya, H. Zhang, E. Dunayevich, D. Haubenberger (Houston, USA)

    Objective: To present safety and efficacy results from a long-term study of once-daily valbenazine for chorea associated with Huntington’s disease (HD). Background: In a 12-week…
  • 2025 International Congress

    Adult-Onset Post-Pump Chorea: A Rare Manifestation Post-Cardiac Surgery in a Puerto Rican Patient

    E. Pérez-Luciano, C. Morfi-Pagán, D. Lozada-Figueroa, L. Surillo-Dahdah (Ponce, Puerto Rico)

    Objective: To report the first case of adult-onset post-pump chorea in Puerto Rico and raise awareness of our patient’s atypical age and onset of clinical…
  • 2025 International Congress

    Real-World Experiences with VMAT2 Inhibitors in Pediatric Hyperkinetic Movement Disorders

    S. Manohar, J. Jacobe, R. Berger, J. Jankovic, M. Hull (Houston, USA)

    Objective: We review the real-world prescribing practices and patient experiences with VMAT2 inhibitors in children. Background: Vesicular monoamine transporter 2 (VMAT2) inhibitors are often prescribed…
  • 2025 International Congress

    Physical, Mental, and Socioemotional Functional Improvement Following Valbenazine Treatment for TD: a Case Series

    R. Bera, J. Nedzesky, I. Gandayuwana, D. Winkelman, D. Vanderhoef, M. Bron, M M. Perez-Rodriguez (San Diego, USA)

    Objective: Describe clinical characteristics and changes in mental, socioemotional, and physical domains of individuals with tardive dyskinesia (TD) after valbenazine (VBZ) treatment. Background: Prior research…
  • 2025 International Congress

    Striatal Dysfunction in Parkinson’s Disease Progression: A 18F-9-fluoropropyl-(+)-dihydrotetrabenazine(18F-AV133) PET Study

    X. Liu, G. Tamagnan, H. Qiao, J. Lu, C. Zhang, S. Liu (Beijing, China)

    Objective: To investigate the patterns of striatal 18F-AV133 uptake in relation to disease progression across different stages of PD and to examine its relationship with…
  • 2024 International Congress

    Evaluating the association between cognitive impairment and striatal VMAT2 binding using [18F]AV-133 PET in Parkinson’s disease

    K. Hwang, J. Langley (Long Beach, USA)

    Objective: To evaluate the association between cognitive deficits and striatal vesicular monoamine transporter type 2 (VMAT2) binding in participants with Parkinson’s disease (PD) using [18F]AV-133…
  • 2024 International Congress

    Comparing 18F-AV133 VMAT2 PET and DATscan as Markers of Parkinson’s Disease Severity and Progression

    M. Miyasaka, A. Avbersek, M. Ahmed, M. Effendi, O. Harari, L. Pham, S. Somersan-Karakaya, L. Sun, O. Levy, F. Sepehrband (Tarrytown, USA)

    Objective: Compare VMAT2 PET signal with DATscan at baseline and over time, and evaluate their correlations with MDS-UPDRS III. Background: DATscan is a Parkinson’s disease…
  • 2023 International Congress

    The effect of APOE ε4 on striatal vesicular monoamine transporter-2 density in Parkinson’s disease

    W. Li, R. Li, J. Lu (Beijing, China)

    Objective: To evaluate the effect of apolipoprotein E 4 (APOE 4) on striatal vesicular monoamine transporter-2 (VMAT2) density in Parkinson’s disease (PD).To evaluate the effect…
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