Instability after MRIg-FUS thalamotomy: why does it appear?
Objective: To know the semiological characteristics and physiopathology of instability after thalamotomy with Magnetic Resonance image guided focused ultrasound thalamotomy (MRIg-FUS). Background: Gait instability is…KINETIC 2: An ongoing phase 2b, randomized, dose-response study of SAGE-324/BIIB124 for the treatment of essential tremor
Objective: KINETIC 2 (NCT05173012) is an ongoing, phase 2b, randomized, double-blind, placebo-controlled, dose-response study that aims to evaluate the efficacy, safety, and tolerability of SAGE-324/BIIB124…Design of a Phase 2 Study of Suvecaltamide in Moderate to Severe Parkinson’s Disease Tremor
Objective: Describe the design of a phase 2 study (NCT05642442) of a once-daily, extended-release formulation of suvecaltamide to treat moderate to severe Parkinson’s disease tremor…Patient experiences in essential tremor: mapping functional impacts to existing measures using qualitative research
Objective: To understand patient experience in essential tremor (ET), describe meaningful concepts related to treatment benefit, and compare concepts to existing clinical outcome assessments (COAs).…Weighing tremor reduction and side effects: Impact of efficacy and safety outcomes on patient satisfaction at 6 months in MR-guided focused ultrasound thalamotomy for tremor treatment
Objective: To relate efficacy and safety outcomes to patient satisfaction at 6 months after MR-guided focused ultrasound (MRgFUS) thalamotomy in the ventral intermediate nucleus (VIM)…A single centre retrospective study of dual target deep brain stimulation for clinically complex essential and dystonic tremor – a 5-year follow up
Objective: Measure efficacy of dual target deep brain stimulation in pharmaco-refractory tremors. Background: Tremor is characterised by involuntary rhythmic movement present in one or more…Axial tremor response to tractography-defined focused ultrasound thalamotomy for essential tremor: a prospective study
Objective: To analyse the effects of unilateral magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy defined by 4-tract tractography on axial tremor at 6 months in patients…Istradefylline effect on Parkinson’s Disease Tremor, Motor symptoms and non-Motor symptoms.
Objective: Istradefylline is FDA approved for use in patients with PD treated with carbidopa-levodopa to reduce off time. GUH Movement Disorder Group has observed that…Neuropsychological Outcomes After Bilateral Focused Ultrasound Thalamotomy within Essential Tremor
Objective: The objective of the study was to elucidate the neuropsychological outcomes in executive functioning for patients with essential tremor undergoing bilateral MRI guided Focused…Transcranial static magnetic field stimulation of the primary motor cortex in essential tremor
Objective: To test the acute therapeutic effects of transcranial static magnetic field stimulation (tSMS) of the primary motor cortex in patients with essential tremor. Background:…
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