Plasma transferrin level correlates with the tremor-dominant phenotype of Parkinson’s disease
Objective: To examine plasma iron metabolism related indicators in patients with Parkinson’s disease (PD) and investigate the mechanism underlying the tremor-dominant phenotype of PD. Background:…Distinguishing isolated asymmetric limb tremor from essential tremor: An electrophysiological study
Objective: The aim of this study was to investigate the somatosensory discrimination threshold (STDT), the short intracortical inhibition (SICI) and the cortical plasticity via paired…Tremor in motor neuron disease may be central rather than peripheral in origin
Objective: To investigate the pathophysiology of action tremor in motor neuron disease (MND). Background: MND refers to a spectrum of degenerative diseases affecting motor neurons.…Association between peripheral inflammation and DATSCAN data of the striatal nuclei in different motor subtypes of Parkinson Disease
Objective: This work was designed to investigate peripheral inflammation in terms of Neutrophil-Lymphocyte ratio (NLR) concerning loss of dopaminergic uptake in caudate and putamen on…Microstructural Changes in Normal Appearing White Matter in Parkinson’s Disease (PD) Correlate with Motor, Tremor, and Neuropsychiatric Scores
Objective: To determine if microstructural changes in the normal appearing white matter of PD are associated with clinical manifestations of disease. Background: White matter (WM)…Prism adaptation and cerebellar inhibition were impaired in essential tremor
Objective: We aimed to reveal cerebellar dysfunction in patients with essential tremor using neurophysiological methods. Background: Cerebellar dysfunction is suggested to contribute to tremor generation.…Cerebello-cortical loops differ between Essential-, Parkinsonian- and voluntary tremor
Objective: Topographical comparison of subcortico-cortical oscillating loops between different tremors. Background: Cerebellum and cortical motor regions are involved in Essential, Parkinsonian and voluntary tremor, three oscillatory motor…Characteristics of tremor caused by non-olivary lesion of the medulla oblongata
Objective: We examined the characteristics of tremor caused by lesions of the medulla oblongata, which do not affect the inferior olive. Background: The medulla oblongata…TETRAS applicability and study design in randomized, placebo controlled clinical trial of Cav3 modulation for essential tremor patients.
Objective: We will study CX-8998, a selective Cav3 antagonist with safety data in 194 patients, in the treatment of ET. Few large controlled ET trials…Effect of L-DOPA on re-emergent tremor in Parkinson’s disease: A neurophysiological assessment
Objective: To conduct a neurophysiological analysis on the postural re-emergence of tremor in PD patients during an acute L-DOPA challenge test. Background: Some patients with…