Fragile X Associated Tremor and Ataxia Syndrome (FXTAS) presents with widespread reactive gliosis and white-matter specific astrocyte degeneration
Objective: We will characterize neuropathological alterations of astrocytes in different regions of the FXTAS brain. Background: FXTAS is a progressive neurodegenerative disorder that occurs in…Metabolic profile in the brain with Fragile X-associated Tremor/Ataxia Syndrome (FXTAS)
Objective: We analyzed changes in the concentration of primary metabolites in post-mortem brain samples from FXTAS cases. We also investigated how these changes relate to…Use Of Digitizing Tablet For the Tremor Evaluation
Objective: This review was done to know the uses of digitalizing tablets for the tremor evaluation. Background: Tremor is the most common movement disorder seen…Validation of postural tremor model using regression and optimization
Objective: The purpose of this work is to validate a mathematical model of postural tremor to predict tremor at the hand from measurements of tremorogenic…Can a “Shopping bag Tremor” be a Pre-diagnostic sign of Parkinson’s Disease?
Objective: To describe an unusual wrist tremor according the existing classification and discuss its aetiological diagnosis. Background: Although Parkinson’s disease (PD) is usually associated with…The pathophysiology of dystonic tremors and comparison with essential tremor
Objective: To explore the pathophysiology of dystonic tremors (DT) and comparison with essential tremor (ET). Background: The characteristics and mechanisms of tremor in dystonia are…Large-Scale Network Changes in the Pathophysiology of Essential Tremor
Objective: To assess functional brain network architecture in participants with medically-refractory essential tremor (ET) and to correlate the strength of these networks with clinical tremor…White matter microstructural abnormalities in tremor dominant and non-tremor dominant Parkinson’s disease
Objective: To explore differences in white matter microstructural integrity in tremor dominant and non-tremor dominant Parkinson’s disease (PD) using tract based spatial statistics (TBSS). Background:…Genetic analysis of DNA methylation and hydroxymethylation genes in Parkinson’s disease
Objective: To investigate the relationship between DNA methylation/hydroxymethylation genes and Parkinson’s disease (PD), we conducted genetic analysis in a relatively large Chinese population. Background: PD…Examining supplementary motor area-primary motor cortex connectivity in tremor-dominant Parkinson’s disease using a novel transcranial magnetic stimulation protocol to inform clinical practice
Objective: Objectives: (1) Measure test re-test reliability of dual-coil transcranial magnetic stimulation (TMS) measures of supplementary motor area-primary motor cortex connectivity (SMA-M1 connectivity). (2) Investigate…