Efficacy of Clonidine for Tourette Syndrome: An Updated Meta-Analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy of Clonidine in reducing tic severity and improving global clinical outcomes in patients with Tourette syndrome. Background: Tourette syndrome is a neurodevelopmental disorder…Dual Target Bi Pallidal Deep Brain Stimulation in Tourette Syndrome Deciphering Neurophysiology with Chronic Local Field Potential Recordings
Objective: To investigate the neurophysiological activity of dual-target bi-pallidal DBS in Tourette Syndrome (TS) patients using chronic local field potential (LFP) recordings in an outpatient…Safety and Tolerability of Ecopipam in Tourette Syndrome (TS) with Psychiatric Comorbidities.
Objective: Evaluate the effect of ecopipam in children and adolescents with TS on measures of attention deficit disorder (ADHD), anxiety disorders (ANX), obsessive-compulsive disorder (OCD)…Ecopipam does not adversely affect Metabolic Parameters in Pediatric Subjects with Tourette Syndrome: Results from a Phase 2b with 12-month Open Label Extension Study
Objective: Determine if ecopipam is associated with the emergence of clinical features suggestive of metabolic syndrome in pediatric subjects with Tourette Syndrome (TS) Background: Dopamine-2…Pregnancy in Dystonia or Tourette’s patients with DBS. Eleven New Cases and a Review of the Literature.
Objective: To review the available literature on pregnancy in patients who have received deep brain stimulation (DBS) for dystonia or Tourette’s syndrome (TS). Background: DBS…How Local Field Potencial could improve GPi Deep Brain Stimulation programming in Tourette`s Syndrome – Case Report
Objective: We report a case of a young woman with refractory severe TS treated with DBS on anterior globus pallidus internus. Background: The Tourette Syndrome…Deep Brain Stimulation in Tourette Syndrome: Characteristics of Three Patients Pre and Post Implantation
Objective: To elucidate how deep brain stimulation (DBS) for Tourette’s syndrome (TS) impacts psychiatric comorbidities including attention-deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), anxiety, and depression.…Effect of Ecopipam, a Selective Dopamine-1 Receptor Antagonist, on Tic Characteristics as Assessed by the YGTSS: Results from a Phase IIb Randomized, Double-blind, Placebo-controlled Clinical Trial in Tourette Syndrome
Objective: Assess the effect of ecopipam treatment on motor and phonic/vocal tic characteristics: number, frequency, intensity, complexity, and interference comprising the Yale Global Tic Severity…Randomized Controlled Trial of Supplementary Motor Area Transcranial Direct Current Stimulation in Tourette Syndrome
Objective: To investigate the effect of cathodal transcranial direct current stimulation (tDCS) over the supplementary motor area (SMA) on tic severity in Tourette syndrome (TS).…Gaps in Diagnosing and Treating Tic Disorders in Latin America: A Survey of Healthcare Workers
Objective: The objective of this study was to investigate the knowledge, treatment, and diagnosis pathways followed for Tic Disorders across Latin America. Background: Tic disorders…
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