New evidence for thalamic dysfunction in Parkinsonian rats
Objective: Abnormal oscillatory activity within the cortico-basal ganglia (BG)-thalamo-cortical circuit has been observed in Parkinsonian state, especially of β and γ bands (βB and γB).…Transient loss of psychic self-activation following bilateral thalamic ventral intermediate nucleus stimulation for essential tremor
Objective: To report a case. Background: Loss of psychic self-activation or even akinetic mutism has rarely been described in patients who suffered bilateral thalamic insults.…Successful deep brain stimulation treatment of incapacitating tremor resulting from bilateral thalamic infarcts complicating surgery for Arnold Chiari malformation/syringomyelia.
Objective: To describe the clinical features of tremor associated with thalamic infarcts and its treatment with thalamic Deep Brain Stimulation (DBS). Background: Delayed onset involuntary…Novel Programming Strategy to Overcome Loss of Efficacy in Essential Tremor
Objective: A review of programming strategies to maintain tremor suppression adequate for functional satisfaction. Background: Deep brain stimulation (DBS) is FDA approved for Essential tremor since…Astasia, reach and grasp deficits following bilateral medio-dorsal pulvinar lesions
Objective: Analysis of the consequences of bilateral dorso-medial pulvinar lesions Background: Expansion of the dorsal pulvinar in humans and its anatomical connectivity suggests its involvement…Improvement Observed in Children with combined GPi and VL Thalamus Deep Brain Stimulation for the Treatment of Secondary Dystonia
Objective: To present 5 children with Gpi and VL thalamus Deep-Brain Stimulation for treatment of secondary dystonia. Background: The target for deep brain stimulation (DBS) in…Non-motor symptom burden is associated with thalamic atrophy in Parkinson’s disease
Objective: To investigate whether non-motor symptoms burden is associated with cortical and subcortical morphological changes in PD patients. Background: Non-motor symptoms are common aspects of…Dopamine reduces Parkinson’s tremor through increased thalamic inhibition
Objective: To identify cerebral mechanisms explaining the effects of dopamine on rest tremor in Parkinson's disease. Background: Resting tremor in Parkinson's disease is related to…Changes of brain structure and cognition in individuals with possible prodromal Parkinson’s disease
Objective: Investigating brain structure and cognition in healthy individuals with positive Parkinson's disease (PD) risk markers (hyposmia, increased hyperechogenic area of the substantia nigra). Background:…Increasing placebo response in Parkinson’s disease through apomorphine pre-conditioning
Objective: To see whether a placebo response requires pharmacological pre-conditioning with apomorphine. Background: Placebos have been found to affect the patient's brain in a number…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.