CSF biomarkers in neurodegenerative parkinsonism can distinguish between multiple system atrophy and 4-repeat tauopathies, but not between disease with Lewy bodies and multiple system atrophy
Objective: To assess the usefulness of a defined set of blood-based and cerebrospinal fluid-based biomarkers in the differential diagnosis of neurodegenerative proteinopathies. Background: The diagnostic…Complications in Patients with Progressive Supranuclear Palsy
Objective: This study elucidated the incidence and features of complications in patients with progressive supranuclear palsy (PSP). Background: PSP is a progressive neurodegenerative disorder accompanied…Pan India Registry for Progressive Supranuclear Palsy (PAIR-PSP)
Objective: To understand Progressive Supranuclear palsy (PSP) phenotype and genotype from India. Background: Insights into PSP pathophysiology and newer clinical phenotypes are increasingly being recognized.…Plasma p-tau181 is increased in Lewy body dementia and relates to cognitive performance
Objective: To compare plasma p-tau181 concentration in Parkinson’s disease (PD), Lewy body dementia (LBD) and healthy controls and to examine the relationship between ptau-181 concentration…In-vivo measurement of tau depositions in anti-IgLON5 disease with 18F-PI2620-PET
Objective: The aim of the study was to examine the potential of the second-generation tau-PET tracer 18F-PI2620 to detect tau deposition in anti-IgLON5 disease. Background:…Lateralized Tau Pathology in a Case of Lewy Body Dementia with Corticobasal Syndrome
Objective: To measure bilateral in vivo and postmortem tau pathology in a well-characterized patient presenting with corticobasal syndrome (CBS) due to underlying neocortical stage Lewy…MAPT mutation frontotemporal dementia with parkinsonism: when previous results can skew the diagnosis
Objective: Case report presentation. Background: In frontotemporal dementia with parkinsonism (FTDP), several mutations in MAPT gene have been identified, and numerous family cases were reported,…In vivo relationship between synaptic density and functional connectivity in progressive supranuclear palsy: a multimodal [11C]UCB-J PET and resting state fMRI study.
Objective: To assess the relationship between synaptic density and functional connectivity in the primary tauopathy of Progressive Supranuclear Palsy (PSP). Background: PSP is a debilitating…Visualising tau in patients with progressive supranuclear palsy using PI2620-PET
Objective: This study investigates the use of a new tau-specific PET radiotracer, [18F]-PI-2620, as a tool for visualising tau in the living brain. Background: The…Novel Cognitive Markers for Early Diagnosis and Monitoring of Progressive Supranuclear Palsy
Objective: The aim of this study was to evaluate whether a novel computerised test could offer an inexpensive and reliable tool that can aid diagnosis…
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