Self-reported demographic, genetic, symptom, and treatment data of subjects in the Fox Trial Finder
Objective: To examine the characteristics of subjects within the Fox Trial Finder (FTF) database. Background: FTF is an online, patient driven database by which Parkinson’s…Applicability of questionnaires and study of the prevalence of REM Sleep Behavior Disorder (RBD) in Parkinson’s disease
Objective: Evaluation of patients with idiopathic Parkinson's disease regarding the presence of RBD, application of the questionnaires, and correlation between the diagnosis of RBD by…Amplification of α-synuclein aggregates in cerebrospinal fluid by rapid ultrasonication-based assay
Objective: To apply an ultrasonication-based misfolded protein amplification to the evaluation of α-synuclein aggregates in CSF, and to investigate their clinical significances in Parkinson’s disease…Arterial spin labelling detects subcortical hypoperfusion in early drug-naïve patients with Parkinson’s disease
Objective: We evaluated regional cerebral blood flow (CBF) levels in a cohort of early drug-naïve patients with Parkinson’s disease, and we explored for associations between…Fine-mapping of SNCA variants in REM sleep behavior disorder identifies distinct associations
Objective: a). Identify variants in the SNCA locus which affect risk for REM Sleep Behavior Disorder (RBD). b). Test variant effects on rate and type…Evidence of altered Serotonergic Network in Parkinson’s disease by using a multi-modal MRI and PET imaging approach
Objective: This study aims to assess how serotonergic pathological derangement may produce alterations in Parkinson’s disease (PD) functional connectivity, by means of a multimodal neuroimaging…The role of LRP10 mutations in Parkinson’s Disease and Dementia with Lewy Bodies
Objective: To test LRP10 in a cohort of Italian patients, with a clinical diagnosis of either Parkinson’s Disease (PD) (n=316) or Dementia with Lewy Bodies…Cortical and subcortical atrophy in typical and variant Parkinson-plus syndromes: PROSPECT-M-UK study
Objective: To investigate grey matter volume in typical and variant Parkinson-plus syndromes, to correlate these with disease severity, and to assess regional atrophy within disease…Evaluation of corneal parameters in patients with idiopathic REM Sleep Behavior Disorder
Objective: To evaluate the blink rate (BR), tear function, and, corneal parameters of patients with iRBD. Background: In patients with Parkinson's disease (PD), dry eye…Long-term changes in myocardial sympathetic innervation and function in synucleinopathies
Objective: Describe long-term trends in indices of cardiac sympathetic innervation and function in synucleinopathies. Background: A group of neurodegenerative diseases including Parkinson disease (PD), pure…
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