Subcortical involvement in phonological input processing: an electrophysiological registration study
Objective: The current study applied direct electrophysiological registration of the local field potential activity in the thalamus, subthalamic nucleus (STN) and the pedunculopontine nucleus (PPN)…Degree, onset and longevity of benefit achieved with Deep Brain Stimulation (DBS) of the subthalamic nucleus (STN) as assessed by the UPDRS.
Objective: To show the degree, onset and longevity of benefit achieved with STN DBS at our center. Background: At our center, we administer the UPDRS-III…The Volatility of Local Field Potential Oscillations in Dystonia and Parkinson’s disease
Objective: To assess the volatility of low frequency (4-12Hz) and beta-band (13-30Hz) oscillations in local field potentials (LFPs) in dystonia and compare this to LFPs…Information transfer between subthalamic area and forearm muscles during tonic muscle activity in Parkinson’s patients
Objective: We compare information transfer between forearm muscles and two subthalamic regions, namely the subthalamic nucleus (STN) and the zona incerta (ZI), during an isometric…UPDRS benefit from dual frequency DBS fields sculpted by intentionally overlapped interleaving
Objective: We show that UPDRS-III scores after interleaving compared to those prior to interleaving reflect a gain in benefit by lowered scores. Background: Previously, we…Outcomes of a Prospective, Multicenter International Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: To investigate the effectiveness and safety-related real-world outcomes of a multiple-source, constant current Deep Brain Stimulation (DBS) System in the treatment of levodopa-responsive Parkinson’s…Efficacy and tolerability of low-frequency deep brain stimulation during daytime only in Parkinson’s disease: a pilot study
Objective: To compare the efficacy and tolerability of low-frequency stimulation (LFS) during daytime only to LFS applied 24 hours a day, in PD patients bilaterally…Real World Clinical Outcomes Using a Novel Directional Lead from a Multicenter Registry of DBS for Parkinson’s disease
Objective: To evaluate clinical outcomes in subjects implanted with a Directional Lead for use in the treatment of levodopa-responsive Parkinson’s disease (PD) as part of…A new tool to measure the impact of deep brain stimulation on Parkinson’s disease patients: Development and validation of the deep brain stimulation impairment scale (DBS-IS)
Objective: To develop a questionnaire that measures impairments related to deep brain stimulation (DBS). Background: DBS has considerable influence on motor and non-motor symptoms in…Implantable pulse generator (IPG) longevity decreases following each replacement surgery in Parkinson’s disease (PD) patients treated with bilateral sub-thalamic nucleus deep brain stimulation (STN-DBS)
Objective: To investigate the influence of the number of implantable pulse generator (IPG) replacement surgeries and the IPG model on battery life in bilateral STN…
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