Variability in the ideal target of GPi DBS for Parkinson’s disease requires advanced direct targeting for optimal results
Objective: Our findings have the potential to transform the clinical practice of surgeons who rely solely on indirect targeting, by raising awareness of the anatomic…Recruitment of single subthalamic neurons for kinematic control of hand and feet movements employs different strategies
Objective: To understand single unit recruitment strategies for upper and lower extremity movements in the human subthalamic nucleus (STN), which is the main target for…Evaluation of the accuracy of stereotactic DBS electrode implantation by post-operative image fusion
Objective: The precision in implantation of deep brain stimulation (DBS) electrodes based on pre-operative MRI planning is of utmost importance for the success of this…DBS of the STN in 44 patients with Parkinson’s disease – Radiological and clinical outcome
Objective: Precision in implantation of deep brain stimulation (DBS) electrodes relies on systematic interdisciplinary planning and intra-operative testing and needs to be discussed along with…Increasing placebo response in Parkinson’s disease through apomorphine pre-conditioning
Objective: To see whether a placebo response requires pharmacological pre-conditioning with apomorphine. Background: Placebos have been found to affect the patient's brain in a number…A dopamine-dependent activity of the STN in the control of balance in Parkinson’s disease
Objective: To investigate the activity of the subthalamic nucleus (STN), and its relation to nigro-striatal dopaminergic denervation, in control of balance in Parkinson's disease (PD).…Reduction in battery longevity for each subsequent implantable pulse generator (IPG) in patients with Parkinson’s disease (PD) treated with bilateral subthalamic nucleus deep brain stimulation (STN-DBS) may be due to both programming changes and IPG model – a case series
Objective: To determine whether the decrease in longevity following IPG replacement is due to programming changes and whether there is an effect of IPG model.…Modulation of local field potentials during gait in the STN of patients with Parkinson’s disease
Objective: PD patients with implanted DBS electrodes allow for the investigation of basal ganglia activity during gait. Background: Whereas the overall spectral content of local…Cortical and subcortical contribution in the production of reaching movements in Parkinson’s disease
Objective: To investigate the interplay between subthalamic nucleus (STN) activity and striatal dopamine deficiency in the production of arm movements in subjects with Parkinson's disease…Suggested protocol for electroconvulsive therapy for depression in a Parkinson’s disease patient with a deep brain stimulator: A case report
Objective: To report an evidence for safety of ECT in patients with DBS in place. Background: We report a case of bilateral electroconvulsive therapy (ECT)…
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