Microelectrode recording for optimization of the long-term outcome in subthalamic deep brain stimulation for Parkinson’s disease
Objective: To evaluate influence of microelectrode recording (MER) on clinical outcome of subthalamic deep brain stimulation (DBS STN) in patients with Parkinson's disease (PD). Background:…DIRECT DBS: A Prospective, Multicenter Clinical Study with Double-Blinding for a Directional Deep Brain Stimulation Lead – Intra-visit Impedance Changes
Objective: To evaluate impedance changes throughout the course of a programming visit as a part of a larger directional lead exploration study. Background: Historically, DBS…Blinded acute assessment of electrode contact efficacy compared with contact location for Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s Disease
Objective: This study aimed to assess the clinical efficacy of each contact and the correlation between the clinical best contacts and radiologically defined optimal contacts.…Quantitative assessment of the effectiveness of adaptive Deep Brain Stimulation in Parkinson’s disease
Objective: To determine the effectiveness of Adaptive Deep Brain Stimulation (aDBS) in PD patients compared to cDBS and non-medicated PD patients (OFF). Background: aDBS based…STN-DBS causing persistent dyskinetic movements in OFF-State
Objective: Transient choreatic movements are known as side effects of DBS of the dorsolateral STN in Parkinson disease (PD). Persistent “brittle” dyskinesia have been reported…Contribution of ATP-sensitive potassium channels in the subthalamic nucleus neurons towards Parkinson’s disease
Objective: This study describe a quantitative investigation to explore the modulating effects of the ATP-dependent Potassium channel (KATP) ion channel conductance on spike patterns in…Phenomenology and management of subthalamic stimulation-induced dyskinesia in a video case series of patients with isolated dystonia
Objective: To document with videotaped observations, 3 patients with isolated dystonia who experienced stimulation-induced dyskinesia (SID) following subthalamic nucleus (STN) deep brain stimulation (DBS). Background:…The Effect of Short Pulse Width Settings on Speech in Subthalamic Nucleus Deep Brain Stimulation for Parkinson’s disease
Objective: To compare perceptual characteristics and intelligibility of speech in Parkinson's Disease (PD) patients with Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) in the acute setting…Determinates and predictors of quality of life improvements after subthalamic deep brain stimulation in Parkinson’s disease
Objective: To detect the related factors and possible predictors to QoL improvement for those PD patients one year after STN DBS. Background: Subthalamic deep brain…STEEred vs RING-mode Deep Brain Stimulation for Parkinson’s disease: STEERING trial
Objective: To evaluate whether directional STN DBS is more effective than ring-mode DBS in reducing PD motor symptoms, and to investigate if directional STN DBS…
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