Toward optimized nonlinear deformation algorithms for subcortical DBS target regions in MRI
Objective: 1. To evaluate and optimize subcortical accuracy of commonly used nonlinear deformation algorithms. 2. To optimize accuracy of automated atlas-based segmentation of the two…Evaluation of apathy before and after subthalamic nucleus deep brain stimulation therapy in advanced Parkinson’s disease patients
Objective: Deep brain stimulation (DBS) has been approved to relieve the motor symptoms of Parkinson's disease (PD) patients when the optimal pharmachologic treatment is unsatisfactory.…Levodopa and subthalamic stimulation do not have the same effect on subjective cost for distal and axial efforts in Parkinson’s disease
Objective: To compare the effects of levodopa and subthalamic nucleus stimulation (STN-DBS) on decision-making tasks for distal (hand) and axial (speech) efforts in Parkinson’s disease…Directional Deep Brain Stimulation: First experiences in centers across the globe
Objective: To evaluate how clinicians are implementing directional DBS technology in their routine care. Background: Directional DBS is a new technology, which increases the clinician’s…Spontaneous peri-electrode edema, 7 years after subthalamic nucleus deep brain stimulation (STN-DBS) in a patient with Parkinson´s disease (PD): A case report
Objective: To describe an infrequent and late complication of STN-DBS in a patient with PD. Background: DBS is a safe procedure for patients with PD.…Quantitative Keyboard Tapping Measurement Correlates with Electrophysiological Changes in STN LFPs of PD Patients Treated with L-dopa Better Than UPDRS Subscores
Objective: Reliable and objective assessment of the symptoms of patients with Parkinson’s disease (PD) and the correlation of the measures with neural patterns is important…DIRECT DBS: A Prospective, Multicenter Clinical Study with Double-Blinding for a Directional Deep Brain Stimulation Lead – Visualization of Optimal Directionally Stimulated Anatomy
Objective: To visualize the volumes of activated tissue in relation to the neuroanatomy for the optimal stimulation parameters in Ring Mode (omnidirectional) stimulation in comparison…Gradient-like representation of emotional valence and arousal within the subthalamic nucleus in Parkinson’s disease
Objective: We aimed to analyze the relationship between the active electrode position within the subthalamic nucleus (STN) and subjective emotional experience in Parkinson’s disease (PD)…Depression, apathy, fatigue in Parkinson with or without STN DBS
Objective: To determine the prevalence of depression, evaluate the relationship between depression, apathy and fatigue, and the impact of STN DBS on the same symptoms.…Directional Lead Impedances and Their Possible Effects on Deep Brain Stimulation
Objective: The objective was to characterize the possible effects that directional leads impedances have on Deep Brain Stimulation (DBS) therapy. Background: DBS of the subthalamic…
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