The volume of STN tissue activated by DBS and the strength of its structural connectivity with SMA predicts the effects of STN-DBS on response inhibition
Objective: To test the hypothesis that antidromic activation of the hyperdirect pathway might mediate the effects of STN-DBS on movement initiation control. Background: In PD,…Real-World Deep Brain Stimulation Outcomes Using Directional DBS Systems with Multiple Independent Current Control
Objective: Here, we report the real-world clinical outcomes associated with the use of DBS systems capable of directionality and Multiple Independent Current Control (MICC) in…Inter-Electrode Distance influences the phase-amplitude coupling (PAC) of Bipolar Subthalamic Local Field Potentials Recordings in Parkinson’s Disease
Objective: This study aimed to assess phase-amplitude coupling (PAC) between two local field potential (LFPs) signals captured from both wide- and close-spaced contact pairs (i.e.…The role of genetics in patient selection and outcomes of deep brain stimulation in Parkinson’s disease
Objective: Determine the role of genetic factors in selecting candidates for, and evaluating outcomes of, deep-brain stimulation (DBS) within the framework of the multi-national Genetic…Inter-Electrode Distance Influences the Spectral Power of Subthalamic Bipolar Local Field Potentials Recordings in Parkinson’s Disease
Objective: This study aimed to evaluate spectral dissimilarities and their correlations with clinical symptoms of intra-operative local field potentials (LFP) acquired from wide- and close-spaced…Visualization Tool for DBS Programming with a Multiple Source, Constant Current System Reduces Initial Programming Time
Objective: We describe utilization of newly available visualization software for use as a Deep Brain Stimulation (DBS) planning tool during initial programming of patients with…LFP spectral features associated with therapy complications in typical and early onset Parkinson’s disease
Objective: The aim of this study was to search for potential markers in the subthalamic nucleus activity of parkinsonian patients associated with levodopa-induced dyskinesias in…Decrease in STN high frequency activity after microelectrode insertion during DBS surgery for Parkinson’s disease
Objective: To examine the effects of microelectrode penetration into the STN on local field potential recordings in patients with PD undergoing bilateral STN DBS implantation.…Beta synchronization of the subthalamic nucleus during self-initiated and externally generated movement in parkinsonian patients in OFF and ON states
Objective: The aim of this study is to estimate the level of beta synchronization of the subthalamic nucleus (STN) evoked by internally and externally generated…Chronic sensing of the subthalamic nucleus in Parkinson’s disease patients: preliminary observations
Objective: Here we document the key advances and pitfalls of the PerceptTM PC (Medtronic), a commercially available device capable of recording brain local field potentials…
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