Outcomes of a Prospective, Multicenter, International Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: Here we report the collected outcomes from a large-scale registry of a deep brain stimulation (DBS) system capable of Multiple Independent Current Source Control…Hyperpolarization of the subthalamic nucleus alleviates hyperkinetic movement disorders
Objective: We test the hypothesis of modulating subthalamic neuronal firing pattern via injection of hyperpolarizing current as an effective treatment for hyperkinetic movement disorders. Background:…Real World Clinical Outcomes Using a Novel Directional Lead from a Multicenter Registry of Deep Brain Stimulation for Parkinson’s Disease
Objective: In this report, initial real-world outcomes using a directional lead with a deep brain stimulation (DBS) system capable of multiple independent current source control…Quantitative Susceptibility Mapping may help distinguish patients with Parkinson’s disease, progressive supranuclear palsy and multiple system atrophy with predominant parkinsonism
Objective: The purpose of this study was to examine quantitative susceptibility mapping (QSM) changes in PD and multiple system atrophy with predominant parkinsonism (MSA-P) and…Directional versus conventional subthalamic deep brain stimulation for advanced Parkinson’s disease: Short-term outcomes of a pilot study
Objective: To investigate efficacy of STN-DBS via segmented directional leads compared to conventional omnidirectional leads in PD-patients. Background: Recently, novel leads which allow stimulation steering in…Increased attention for food stimuli as a mechanism for weight gain in patients with Parkinson’s disease undergoing DBS of the subthalamic nucleus
Objective: The purpose of this study was to investigate effects of STN DBS on food cue viewing and neural processing of food stimuli in PD…Plasticity of frequency dependent tremor control in Parkinson disease (PD) subthalamic nucleus (STN) deep brain stimulation (DBS) implanted individuals
Objective: To document DBS induced frequency parameter neuroplasticity in STN DBS implanted individuals with tremor dominant PD. Background: We have noted the ability to reduce…Can post-operative local field potentials in the STN predict long-term DBS efficacy in Parkinson’s disease?
Objective: To test whether post-operative local field potential recordings in STN could predict the long-term therapeutic efficacy in patients with PD who underwent bilateral STN…Comparison of omnidirectional versus unidirectional STN-DBS – Impact on gait and balance in Parkinson’s disease
Objective: This study was designed to compare the effects of bilateral omnidirectional and unisegmental directional deep brain stimulation in the subthalamic nucleus (STN-DBS) on axial…Rhythmic activity of subthalamic neurons during externally and internally generated movements in Parkinson’s disease
Objective: To find the specificity of neuronal responses in the subthalamic nucleus during externally and internally generated voluntary movements in Parkinson’s disease. Background: The motor…
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