Long-Term Evaluation of Deep Brain Stimulation for Treatment of Parkinson’s Disease Using a Multiple-Source, Constant-Current Rechargeable System: 4-year Follow-Up of a Prospective, Double-Blind RCT
Objective: The long-term effectiveness of a Deep Brain Stimulation (DBS) device capable of Multiple Independent Current Control (MICC) is assessed in a prospective, sham-controlled, double-blind…Comparison of Activa PC to Percepttm impedance assessment across device exchanges
Objective: To document any differences in impedance assessments across neurostimulator models during device exchanges. Background: The Activa PC parameters, with which impedance is measured are…Unilateral Subthalamic Versus Unilateral Pallidal Stimulation in Parkinson’s Disease: A Randomized Double-Blind Crossover Study
Objective: To compare the acute effects of deep brain stimulation (DBS) of unilateral subthalamic nucleus (STN) and unilateral globus pallidus interna (GPi) on motor function…Satisfaction of Parkinson patients, caregivers and clinicians after STN-DBS and its predictors
Objective: To evaluate and compare patients’ and caregivers’ satisfaction with subthalamic nucleus (STN)-DBS and to identify preoperative indicators, which can prove valuable in defining postoperative…The volume of STN tissue activated by DBS and the strength of its structural connectivity with SMA predicts the effects of STN-DBS on response inhibition
Objective: To test the hypothesis that antidromic activation of the hyperdirect pathway might mediate the effects of STN-DBS on movement initiation control. Background: In PD,…Real-World Deep Brain Stimulation Outcomes Using Directional DBS Systems with Multiple Independent Current Control
Objective: Here, we report the real-world clinical outcomes associated with the use of DBS systems capable of directionality and Multiple Independent Current Control (MICC) in…Inter-Electrode Distance influences the phase-amplitude coupling (PAC) of Bipolar Subthalamic Local Field Potentials Recordings in Parkinson’s Disease
Objective: This study aimed to assess phase-amplitude coupling (PAC) between two local field potential (LFPs) signals captured from both wide- and close-spaced contact pairs (i.e.…The role of genetics in patient selection and outcomes of deep brain stimulation in Parkinson’s disease
Objective: Determine the role of genetic factors in selecting candidates for, and evaluating outcomes of, deep-brain stimulation (DBS) within the framework of the multi-national Genetic…Inter-Electrode Distance Influences the Spectral Power of Subthalamic Bipolar Local Field Potentials Recordings in Parkinson’s Disease
Objective: This study aimed to evaluate spectral dissimilarities and their correlations with clinical symptoms of intra-operative local field potentials (LFP) acquired from wide- and close-spaced…Visualization Tool for DBS Programming with a Multiple Source, Constant Current System Reduces Initial Programming Time
Objective: We describe utilization of newly available visualization software for use as a Deep Brain Stimulation (DBS) planning tool during initial programming of patients with…
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