The role of genetics in patient selection and outcomes of deep brain stimulation in Parkinson’s disease
Objective: Determine the role of genetic factors in selecting candidates for, and evaluating outcomes of, deep-brain stimulation (DBS) within the framework of the multi-national Genetic…Inter-Electrode Distance Influences the Spectral Power of Subthalamic Bipolar Local Field Potentials Recordings in Parkinson’s Disease
Objective: This study aimed to evaluate spectral dissimilarities and their correlations with clinical symptoms of intra-operative local field potentials (LFP) acquired from wide- and close-spaced…Visualization Tool for DBS Programming with a Multiple Source, Constant Current System Reduces Initial Programming Time
Objective: We describe utilization of newly available visualization software for use as a Deep Brain Stimulation (DBS) planning tool during initial programming of patients with…LFP spectral features associated with therapy complications in typical and early onset Parkinson’s disease
Objective: The aim of this study was to search for potential markers in the subthalamic nucleus activity of parkinsonian patients associated with levodopa-induced dyskinesias in…Decrease in STN high frequency activity after microelectrode insertion during DBS surgery for Parkinson’s disease
Objective: To examine the effects of microelectrode penetration into the STN on local field potential recordings in patients with PD undergoing bilateral STN DBS implantation.…Beta synchronization of the subthalamic nucleus during self-initiated and externally generated movement in parkinsonian patients in OFF and ON states
Objective: The aim of this study is to estimate the level of beta synchronization of the subthalamic nucleus (STN) evoked by internally and externally generated…Chronic sensing of the subthalamic nucleus in Parkinson’s disease patients: preliminary observations
Objective: Here we document the key advances and pitfalls of the PerceptTM PC (Medtronic), a commercially available device capable of recording brain local field potentials…Nonmotor effects of subthalamic stimulation in Parkinson’s disease motor subtypes
Objective: To compare bilateral subthalamic stimulation (STN-DBS) effects on quality of life (QoL), motor, and nonmotor symptoms (NMS) in ‘tremor-dominant’ and ‘postural instability and gait…Quantitative study of T-type Ca2+ channels in the subthalamic nucleus neurons towards Parkinson’s disease
Objective: From the pathophysiological perspectives, Parkinson’s disease (PD) can be viewed as a prototypical disorder of “brain arrhythmias”. Therefore, the modulation of relevant ion channels…Overcoming Stimulation-Related Side Effects And Improving Outcome By Proper Programing Of Subthalamic Stimulation Of Parkinson’s Disease: Cases Report
Objective: We reported three cases of subthalamic deep brain stimulation (STN-DBS) of Parkinson’s disease (PD), with successful management of challenging issues during programing. Background: Proper…
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