May substantia nigra volume asymmetry be an indicator of motor asymmetry in Parkinson’s disease? A retrospective analysis
Objective: We investigated whether smaller substantia nigra is associated with worse parkinsonism on the corresponding contralateral side. Background: Degeneration of dopaminergic cells and morphologic changes…Transcranial sonography of the substantia nigra and its correlation with iron metabolism and c-reactive protein in Parkinson’s disease
Objective: To measure the echogenicity of the substantia nigra (SN) by transcranial sonography (TCS) in PD patients and discuss its correlation with iron metabolism and…Prognostic factors of motor symptoms in Parkinson’s disease using neuromelanin imaging and the relationship with (123)I-FP-CIT-SPECT
Objective: This study aimed to examine the relationship between findings of neuromelanin sensitive MRI findings and motor complications. We also examined the correlation of findings…Diagnostic value of a new coronal examination plane in transcranial nigral sonography and of additional M-mode tremor frequency determination for the differentiation of idiopathic Parkinson’s disease and essential tremor
Objective: To (1) evaluate a new coronal examination plane in comparison to the established axial examination plane for detection of nigral hyperechogenicity and (2) to…Frequency of echogenic abnormality of the substantia nigra is increased in methamphetamine users
Objective: To investigate structural abnormality of the substantia nigra (SN) in methamphetamine users using transcranial sonography (TCS). Background: Epidemiologic studies suggest that chronic use of…Substantia nigra hyperechogenicity in Parkinson´s disease motor phenotypes
Objective: To evaluate substantia nigra hyperechogenicity (SN+) with transcranial sonography (TCS) in different PD motor subtypes. Background: Parkinson´s disease (PD) patients display a range of…Evolution of mild Parkinsonian signs in a longitudinal population-based cohort
Objective: To investigate evolution of mild Parkinsonian signs (MPS) in an ongoing longitudinal study on Parkinson's disease (PD). Background: Mild motor impairmant may progress to…MRI signatures of the brain of Parkinson’s disease and idiopathic REM sleep behavioral disorder subjects
Objective: To characterize brain microstructural integrity, iron loads, and functional connectivity in 10 idiopathic rapid eye movement sleep behavior disorder (RBD), 10 Parkinson's disease (PD)…Application of the MDS research criteria for prodromal Parkinson’s disease to the longitudinal population-based Bruneck study cohort
Objective: To quantify the prevalence of prodromal phase of Parkinson's disease (PD) defined per 2015 MDS research criteria and their potential to predict incident clinically…Targeted over-expression with AAV-mediated human α-synuclein in a rat model of Parkinson’s disease – Validation of novel fine motor functional effects
Objective: Targeted over-expression of human α-synuclein using viral-vector mediated gene delivery into the substantia nigra of rats and non-human primates has been reported to lead…
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