Ultrasonographic signatures associated with movement disorders (USA-MD study): A population-based longitudinal study
Objective: To identify sonographic biomarkers of PD (Parkinson´s disease). Background: Study of Parkinson’s disease biomarkers could lead us to identify the disease at its earlier…Evaluation of serum sestrin protein in Parkinson’s disease: a plausible diagnostic marker
Objective: In this study, we evaluated the concentrations of sesn1 and sesn2 in the serum of 50 PD patients and 60 elderly controls. Aging is…Cardiac 123I-MIBG Scintigraphy, olfactory testing and transcranial sonography for differentiating between Parkinson’s disease and atypical parkinsonian syndromes during the early stage
Objective: To evaluate the utility of the combined use of cardiac metaiodobenzylguanidine (MIBG) scintigraphy, olfactory testing, and substantia nigra (SN) hyperechogenicity on transcranial sonography (TCS)…A follow-up study of hyperechogenicity of the substantia nigra in Parkinson’s disease and atypical parkinsonian syndrome
Objective: To evaluate whether the hyperechogenic size of the substantia nigra changes with time in Parkinson's disease (PD) and atypical parkinsonian syndromes (APSs), such as…Substantia nigra area evaluated by neuromelanin-sensitive MRI as an imaging biomarker of disease progression in Parkinson’s disease
Objective: to investigate the pattern of substantia nigra - neuromelanin (SN-NM) area loss and contrast ratio (CR) intensity changes in late-stage Parkinson’s disease (LSPD) patients,…High-Pass Filtered Phase MR Imaging to Detect Longitudinal Motor Associations of Iron Accumulation in Parkinson’s Disease
Objective: To assess whether longitudinal changes in deep grey matter nuclei iron content are associated with declining motor function in Parkinson’s disease over a period…Assessing Nigral Functional Connectivity in Parkinson’s Disease with Resting State Functional MRI
Objective: To evaluate functional connectivity of SN with basal ganglia and motor cortex in Parkinson’s disease (PD) using resting state functional MRI (RS fMRI). Background:…Clinical utility of visualization of Nigrosome-1 in patients with Parkinson’s disease
Objective: To determine the inter-rater reliability of Nigrosome-1 detection and its relation to asymmetry of clinical symptoms in Parkinson’s disease (PD). Background: Detection of Nigrosome-1…Volume analysis and localization of midbrain hyperechogenecities via TCS and MRI
Objective: We are presenting follow-up results on our previous study for 3D volumetric measurements of SN hyper-echogenicities, to differentiate PD patients from healthy controls (HC).…Substantia nigra hyperechogenicity in male methamphetamine users
Objective: To investigate the effect of sex on substantia nigra (SN) echogenicity in young-to-middle aged adults with a history of methamphetamine use. Background: The sonographic…
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