Long-term follow up of unilateral focused ultrasound subthalamotomy for the treatment of motor features in asymmetric PD
Objective: To report long-term outcome of unilateral MR-guided focused ultrasound(MRgFUS) subthalamotomy for the treatment of PD cardinal motor features. Background: The development of MRgFUS as…Symptomatic delayed-onset edema following deep brain stimulation for Parkinson’s disease: occurrence, symptoms, management and outcomes. Experience of a single center.
Objective: To report on occurrence, symptoms, management and outcomes of SDE following DBS of either the subthalamic nucleus (STN) or Globus pallidum interna nucleus (GPi)…Combined STN and NBM DBS in PD and mild to moderate Parkinson’s dementia
Objective: While deep brain stimulation (DBS) of the subthalamic nucleus (STN) alleviates Parkinson"s Disease(PD) related motor symptoms, to date PD dementia (PDD) patients are excluded…Does microelectrode recording increase haemorrhage? A comparative study in a large patient cohort over 20 years
Objective: We aimed to investigate whether there is an increased risk of haemorrhage by using microelectrode recording in a large series of patients operated over…Are transventricular approaches associated with increased haemorrhage in functional stereotactic neurosurgery? A comparative study on 550 patients
Objective: We investigate the comparative occurence of haemorrhage with or without transventricular apporaches in a large series of patients operated over two decades. Background: Accurate…Surgery‐related 30-day morbidity of deep brain stimulation in a large cohort of 600 patients
Objective: In this retrospective study we analyzed the surgery‐ and hardware‐related morbidity of deep brain stimulation within 30 days after surgery. Background: 600 functional stereotactic…The SUNRISE-PD Study, a clinical trial of AXO-LENTI-PD: a CNS-directed gene therapy for the treatment of Parkinson’s Disease
Objective: This presentation will provide an overview of the design and key objectives of the SUNRISE-PD study. Background: Parkinson’s disease (PD) is caused in part,…Pediatric Deep Brain Stimulation in Secondary Dystonia using Stereotactic Depth Electrode Targeting
Objective: The primary objective of our pediatric clinical research is to improve outcomes after deep brain stimulation for pediatric patients with secondary dystonia. We apply…Effect of Post-Operative Symptomatic Lead Edema Associated with Subthalamic Deep Brain Stimulation On Clinical Outcomes
Objective: To assess whether development of post-operative symptomatic edema around deep brain stimulation (DBS) leads impacts clinical outcomes. Background: Post-operative symptomatic delayed edema around the…Controlled neural organoids grafting promotes functional recovery in experimental parkinsonism
Objective: We propose that the striatal transplantation of 3D-neural organoids of controlled cell size and cell content, named "Controlled Neural Organoids" (CNOs), could circumvent the…
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