Spiral Tunneling Technique for passing electrode lead for Deep Brain Stimulation(DBS) surgery in Parkinson’s disease(PD)
Objective: To compare the conventional “Twist & Anti-Twist” technique and “Spiral Tunnelling Technique”(STT) for tunnelling the leads for Deep Brain Stimulation surgery in PD. Background:…Post-operative imaging findings in deep brain stimulation
Objective: To study post-operative imaging findings following deep brain stimulation (DBS) and to analyse their association with the patient`s clinical status. Background: DBS is widely…Impact of the COVID-19 pandemic on DBS accessibility: a single center experience
Objective: To evaluate the impact of the COVID-19 pandemic on accessibility to deep brain stimulation (DBS) care at a tertiary DBS center Background: Early responses…Machine Learning Prediction of Motor Score Reduction following DBS Surgery in PD
Objective: This study investigates several machine learning methods for predicting motor score reduction following DBS surgery in patients with PD using multi-modal feature selection. Background:…GDNF Gene Therapy for Parkinson’s Disease (PD): Preliminary Safety and Clinical Findings from a Phase Ib Study
Objective: Assess the safety and tolerability of intraputaminal AAV2-GDNF in mild to moderate PD Background: Glial cell line-derived neurotrophic factor (GDNF) is critical for dopaminergic…Preliminary real-world surgical data collection in RAD-PD
Objective: To describe surgical practices in a cohort of patients with Parkinson’s disease (PD) undergoing deep brain stimulation (DBS). Background: DBS is well-established to improve…Prevention and management of Deep Brain Stimulation (DBS) surgical site infections (SSI) – multicentre survey of UK practice.
Objective: The aim of this survey was to better understand trends, patterns and practices of DBS surgical site care in the UK. Background: Deep brain…Continuous circadian intracerebroventricular administration of anaerobically preserved dopamine greatly reduces severe L-dopa-related complications in Parkinson’s disease
Objective: We aim to demonstrate the safety and efficacy of continuous circadian intracerebroventricular (i.c.v.) administration of anaerobic-dopamine (A-dopamine) to reduce the L-dopa-related complications (LDRC) in…Intraoperative quantification of MDS-UPDRS tremor measurements using 3D accelerometry
Objective: This study focuses on translating parkinsonian tremor tests to an objective method to rate tremor severity using 3D accelerometry, that can be used during…Impact of rs6265 in the Host and Donor on Dopamine Neuron Graft Function.
Objective: Extend investigations into the effect of the rs6265 single nucleotide polymorphism (SNP) on dopamine (DA) neuron graft efficacy using a parkinsonian rat model. Background:…
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