Improving parkinsonism in DBS poor-responders by surgical lead revision of subthalamic electrodes
Objective: If subthalamic deep brain stimulation (STN-DBS) results in poor symptom control or adverse side effects at low stimulation threshold surgical lead revision for optimal…Accuracy of intraoperative CT during DBS procedures: Comparison with postoperative MRI
Objective: To determine the accuracy of intraoperative CT (iCT) in localizing deep brain stimulation (DBS) electrodes by comparing this modality with postoperative magnetic resonance imaging…Speech 10 years post bilateral STN-DBS for Parkinson’s disease
Objective: This study reports on the type and severity of speech problems up to 10 years after bilateral deep brain stimulation (DBS) of the subthalamic…A pilot study of horizontal current steering with chronically implanted segmented electrodes for STN-DBS in Parkinson’s disease
Objective: To evaluate the effect of horizontal current steering using a chronically implanted segmented lead and multiple independent current source technology on clinical effect and…Transcranial unilateral MR guided high intensity focused ultrasound in Parkinson’s disease or essential tremor seems to be save concerning dysphagia and dysarthria
Objective: To report first results of a study monitoring speech and swallowing function after lesional functional neurosurgery for movement disorders. Background: Transcranial MR-guided high intensity…DBS of the STN in 44 patients with Parkinson’s disease – Radiological and clinical outcome
Objective: Precision in implantation of deep brain stimulation (DBS) electrodes relies on systematic interdisciplinary planning and intra-operative testing and needs to be discussed along with…Safety of deep brain stimulation for movement disorders: A single-centre long-term standardized recording and analysis
Objective: To analyze the long-term safety of Deep Brain Stimulation (DBS) procedures for patients with movement disorders. Background: DBS is currently indicated to treat several…Modulation of microglia function in the prion-like spreading of α-synuclein in the murine brain
Objective: We aimed to analyze the influence of two microglia-related pathways on the accumulation of α-synuclein aggregates and neurodegeneration after intracerebral injection of sonicated murine…Piperine potentiates neuroprotective effect of curcumin in MPTP model of Parkinson’s disease in rats: Impact on neurochemical modulation
Objective: (1) Curcumin is well tolerated phenolic compound used for CNS disorder but problem is its low oral bioavailability and (2) Piperine is combined to…Finding an optimal lead trajectory for a better stimulated volume in movement disorder therapy
Objective: Defining the best lead trajectory (Arc; Ring) with a computational 3D stereotactic model of the Globus Pallidus internus (GPi) and investigating the influence of…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.