Utilising multiple murine models to investigate sleep and circadian system dysfunction in PD
Objective: We aimed to investigate the impact of alpha-synuclein aggregation and spreading, and nigrostriatal dopaminergic degeneration on sleep homeostasis and circadian function. Background: Sleep dysfunction…Slow wave activity as a marker of levodopa induced dyskinesia
Objective: To assess the role of slow wave activity during slow wave sleep (SWS-SWA) as a marker of levodopa induced dyskinesia (LID) development in Parkinson's…Impact of Chronotypes and melatonin levels on sleep disorders in patients with Parkinson’s disease
Objective: To investigate the sleep problems and circadian rhythm abnormalities in PD patients using sleep evaluation scale – Parkinsons disease sleep scale (PDSS) for mild…REM density in isolated REM sleep without atonia
Objective: To investigate REM density in patients with isolated REM sleep without atonia. Background: Isolated RSWA (iRSWA) is regarded as a prodromal phase of REM…Augmented Brain Wave Synchronicity in Sleep in Parkinson’s Disease Patients
Objective: Sleep dysfunction in Parkinson’s disease (PD) is a commonly reported symptom. Background: Analysis of brain wave synchronicity may help to unravel this phenomenon and…Modulation of Na+/K+ ATPase activity of rat brain synaptosome by norepinepherine and serotonin
Objective: We tried to study the effect of Norepinepherine and Serotonin on Sodium Potassium ATPase in rat brain synaptosome. Background: Sleep and wakefulness are behavioral…The effects of timed exposure to bright light in improving the gait patterns of patients with Parkinson’s disease – A pilot study
Objective: To investigate the impact of timed exposure to bright light (TEBL) on improving gait function in medicated PD patients with dyskinesias (PD+DYS) and without…Increased Brain-Chin/Leg EEG Synchronicity in Sleep in Parkinson’s Disease
Objective: Sleep dysfunction in Parkinson’s disease (PD) is a commonly reported symptom. Analysis of brain wave synchronicity may help to unravel this phenomenon and serve…Circadian and Homeostatic Modulation of Multi-unit Activity in Dopaminergic and Striatal Structures
Objective: This study aims at investigating the impact of sleep and sleep deprivation on neuronal activity of midbrain dopaminergic areas and different subdivisions of the…Structural connectome of brainstem nuclei in REM sleep behavior disorder, a model of premanifest synucleinopathy
Objective: To investigate in vivobrainstem structural connectivity changes in a model of premanifest synucleinopathy, REM sleep behavior disorder (RBD), using 7 T high spatial-resolution diffusion-tensor-imaging (DTI)…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.