Gerstmann-Straussler-Scheinker Syndrome Manifesting Levodopa-Responsive Parkinsonism, Levodopa-Induced Dyskinesia, and Abnormal DaT-SPECT
Objective: The objective of this report is to describe previously unreported features in a patient with Gerstmann-Straussler-Scheinker syndrome (GSS) due to the F198S mutation. Background:…Correlation between 3 Tesla Brain MRI Nigrosome-1 imaging and SPECT 123I-Ioflupane in parkinsonian disorders
Objective: To correlate nigrosome-1 (NG1) imaging and SPECT 123I-Ioflopane findings to determine the feasibility and diagnostic value of NG1 imaging in a real-world clinical setting.…Diagnostic Utility of I123-FP-CIT Single Photon Emission Computed Tomography for Patients with Clinically Uncertain Parkinsonian Syndrome
Objective: This study investigated the impact of I123-FP-CIT single photon emission computed tomography (SPECT) for the diagnosis of patients with clinically uncertain parkinsonian syndrome (CUPS)…DaTscan striatal binding ratio dynamics in mutations carriers at risk for Parkinson’s disease: A 2-year prospective study
Objective: To investigate the temporal dynamics of striatal binding ratios (SBRs) among individuals with Parkinson's disease (PD)-related mutations and its' association with likelihood ratio (LR)…Serial DaT-SPECT imaging in asymptomatic carriers of LRRK2 G2019S mutation: 8-years follow-up
Objective: To characterize the 8-year progression of clinical and imaging biomarkers in a cohort of asymptomatic LRRK2 G2019S carriers and to assess its utility as predictors of…A direct longitudinal comparison of free water diffusion MRI and DaTscan SPECT in Parkinson’s Disease.
Objective: To compare the within-subject longitudinal sensitivity of PD biomarkers derived from DaTscan and Diffusion MRI. Background: Parkinson’s Disease (PD) is associated with impaired striatal…Aberrant dopamine transporter and functional connectivity patterns in LRRK2 and GBA non-manifesting carriers
Objective: We aimed to study the association between presynaptic striatal dopamine uptake and functional connectivity (FC) patterns among healthy first-degree relatives of PD patients with…DAT-IQ improves power to detect longitudinal change in DaT deficit in SURE-PD3
Objective: DATIQ has been developed as a novel analytical approach to improve the sensitivity and statistical efficiency of dopamine transporter (DaT) SPECT quantification over previously…EVOLUTION OF PARKINSON’S DISEASE IN PATIENTS WITH ESSENTIAL TREMOR: CLINICAL AND NEUROIMAGING ASPECTS
Objective: Analyze the result of the SPECT-TRODAT image exam in patients with ET and to evaluate the predictive value of a possible evolution to the…Striatal dopaminergic loss in early clinically unilateral Parkinson’s disease: a systematic review
Objective: To quantify the extent of dopaminergic loss in early clinically unilateral PD from studies using presynaptic dopamine imaging with either single photon emission computed tomography…
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