Relation between the clinical features and the standardized heart to mediastinum ratio in cardiac metaiodobenzylguanidine imaging in patients with Parkinson’s disease: A multicenter cross-sectional study
Objective: To investigate relation between the clinical features and the standardized heart to mediastinum (H/M) ratio by cardiac metaiodobenzylguanidine (MIBG) imaging in patients with Parkinson's…DAT SPECT data of Parkinson’s disease patients with and without REM Sleep Pathology: A report from the DeNoPa cohort
Objective: To evaluate the DAT SPECT (Single photon emission computerized tomography of the dopamine transporter) parameters for Parkinson's disease (PD) patients with REM Sleep Behavior…Dynamic dopamine transporter images are helpful for diagnosing parkinsonism
Objective: This study is aimed at introducing a new method to get Dopamine transporter (DAT) imaging simultaneously with regional cerebral flow (CBF) imaging. Background: DAT…Nigrostriatal degeneration and serum BDNF levels in patients with “de novo” untreated Parkinson’s disease
Objective: To evaluate serum Brain-Derived NeurotrophicFactor(BDNF) levels in “de novo” untreated Parkinson's disease (PD) patients and their relationship to nigrostriatal degeneration measured with [123I]FP-CIT SPECT.…Levodopa induced dyskinesia and nicotinergic α4β2 acetylcholin receptor density: A multi-tracer imaging study
Objective: We investigated α4β2 acetylcholin receptor (nAChR) density in subjects with Parkinson's disease (PD) with and without levodopa-induced dyskinesia (LID) and its correlation with dopaminergic…Visual vs. automated analysis of [123I]FP-CIT SPECT scans in patients with parkinsonism
Objective: To investigate the differences between visual and automated analyses of brain dopamine transporter (DAT) SPECT scans. Background: Clinical evaluation of DAT SPECT scans typically…Comparison of DAT scan, cardiac MIBG scintigraphy, and cerebrospinal fluid 5HIAA levels in Parkinsonian syndrome
Objective: To assess the associations of presynaptic dopamine transporter (DAT scan), cardiac 123I-meta-iodobenzylguanidine (MIBG) scintigraphy, and cerebrospinal fluid (CSF) levels of 5-hydroxyindole acetic acid (5HIAA)…The efficacy of quantitative 99mTc-TRODAT-1 SPECT in diagnosis of aged patients with Parkinson’s disease
Objective: We aim to establish the normal reference with quantitative 99mTc-Trodat-1 (TRODAT) SPECT and verify the diagnostic performance in aged Parkinson's disease (PD) patients. Background:…Targeted over-expression with AAV-mediated human α-synuclein in a rat model of Parkinson’s disease – Validation of novel fine motor functional effects
Objective: Targeted over-expression of human α-synuclein using viral-vector mediated gene delivery into the substantia nigra of rats and non-human primates has been reported to lead…Study of striatal dopamine transporter function in Alzheimer’s disease with parkinsonism
Objective: To clarify the pathological basis for Alzheimer's disease (AD) with parkinsonism using striatal dopamine transporter (DAT) scan. Background: Pathological basis for parkinsonism in AD…