Comparison of DAT scan, cardiac MIBG scintigraphy, and cerebrospinal fluid 5HIAA levels in Parkinsonian syndrome
Objective: To assess the associations of presynaptic dopamine transporter (DAT scan), cardiac 123I-meta-iodobenzylguanidine (MIBG) scintigraphy, and cerebrospinal fluid (CSF) levels of 5-hydroxyindole acetic acid (5HIAA)…The efficacy of quantitative 99mTc-TRODAT-1 SPECT in diagnosis of aged patients with Parkinson’s disease
Objective: We aim to establish the normal reference with quantitative 99mTc-Trodat-1 (TRODAT) SPECT and verify the diagnostic performance in aged Parkinson's disease (PD) patients. Background:…Targeted over-expression with AAV-mediated human α-synuclein in a rat model of Parkinson’s disease – Validation of novel fine motor functional effects
Objective: Targeted over-expression of human α-synuclein using viral-vector mediated gene delivery into the substantia nigra of rats and non-human primates has been reported to lead…Study of striatal dopamine transporter function in Alzheimer’s disease with parkinsonism
Objective: To clarify the pathological basis for Alzheimer's disease (AD) with parkinsonism using striatal dopamine transporter (DAT) scan. Background: Pathological basis for parkinsonism in AD…A dopamine-dependent activity of the STN in the control of balance in Parkinson’s disease
Objective: To investigate the activity of the subthalamic nucleus (STN), and its relation to nigro-striatal dopaminergic denervation, in control of balance in Parkinson's disease (PD).…Decline in drawing ability associated with frontal dysfunction after subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: The aim of the present study was to elucidate the properties of drawing ability in Parkinson's disease (PD) patients after bilateral subthalamic nucleus deep…Parkinsonism in patients with CADASIL
Objective: To report the clinical manifestation of parkinsonism in patient with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) confirmed by the NOTCH3…Genetic factors influencing frontostriatal dysfunction and the development of dementia in Parkinson’s disease
Objective: To investigate the role of APOE, MAPT, COMT, SNCA and GBA genes in both striatal dopaminergic denervation and the development of dementia in Parkinson's…Depression, anxiety, and apathy in Parkinson’s disease: Insights from neuroimaging studies
Objective: (1) To evaluate the existing neuroimaging studies of depression, anxiety and apathy in Parkinson's disease (PD) and (2) to determine the key neural pathway…Pisa syndrome in a drug-naive Parkinson’s disease patient
Objective: We report on a patient who presented a reversible Pisa syndrome without any dopaminergic treatment at onset and before diagnosis of Parkinson's disease (PD).…