Semiquantitative analyses of DAT-SPECT imaging with an automated striatal analysis software in differential diagnosis of neurodegenerative parkinsonism
Objective: We investigate the usefulness Dopamine transporter (DAT)-SPECT with an automated striatal analysis software in differential diagnosis of neurodegenerative parkinsonism. Background: DAT-SPECT imaging is sensitive…Global Regulatory Agencies Support the Use of Dopamine Transporter Neuroimaging for Subject Selection in Clinical Trials Targeting Early Stage Parkinson’s Disease – on behalf of Critical Path for Parkinson’s (CPP) Consortium
Objective: A key goal of the Critical Path for Parkinson’s Consortium (CPP) is to qualify, with regulatory agencies, drug development tools for use in PD…Multiple modality biomarker prediction of cognitive impairment in prospectively followed de novo Parkinson disease
Objective: To assess the neurobiological substrate of initial cognitive decline in Parkinson’s disease (PD) to inform patient management, clinical trial design, and development of treatments.…Non-motor symptoms in Parkinson’s disease and putamen dopamine transporter uptake (DaTscan) uptake: a survey of 85 patients
Objective: We addressed association between 30 non-motor symptoms (NMS) (using the validated Parkinson’s disease (PD) NMS Scale (NMSS)), and DaTscan putamen uptake ratios as part…Assessment of cognitive impairment using FP-CIT SPECT
Objective: We aimed to assess the cognitive impairment using FP-CIT SPECT in mild cognitive impairment or dementia patients. Background: In general, FP-CIT SPECT reflect pre-synaptic dopamine…Patterns of Striatal DAT Binding Loss in a Progressing Parkinson Disease (PD) Cohort: Four year PPMI Follow-up
Objective: To evaluate within subject striatal changes in dopamine transporter (DAT) binding using 123-I Ioflupane SPECT in PD participants studied over four years in the…Combination of multimodal neuroimaging techniques is useful to diagnose multiple system atrophy
Objective: To determine whether multiple system atrophy (MSA) patients can be differentiated form Parkinson's disease (PD) patients using combination of multimodal neuroimaging techniques. Background: MSA…The Role of MRI and DaTscan in Vascular Parkinsonism: A Case Report
Objective: The role of MRI and DAT scan in Vascular Parkinsonism: A Case Report Background: DaTscan has become a widely used clinical tool to help clinicians…Improved diagnosis of dementia with Lewy bodies by the combination of Tc-99m ECD SPECT with eZIS analysis and quantitative TRODAT-1 SPECT images
Objective: The development of easily useful neuroimaging may resolve to the delays of diagnosis. Background: Dementia with Lewy bodies (DLB) is easy to be misdiagnosed…Voxel-based Analysis of Cholinesterase Inhibitor Response in Lewy Body Disorders: A Prospective Observational Study
Objective: The objective is to investigate functional neuroimaging correlates of response to ChEIs in LBD. Background: Lewy body disorders (LBD), including dementia with Lewy bodies…
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