Quercetin administration abrogates the Parkinson’s disease (PD)-like motor and non-motor symptoms and attenuates the behavioral, neurochemical and biochemical deficits induced by rotenone toxicity in rats
Objective: The present study was carried out to investigate the preventive and therapeutic effects of quercetin (a flavonol) against rotenone-induced neurotoxicity. Background: Rotenone (pesticide) induced…Chlorogenic acid and Trianthema portulacastrum combinational therapy mitigates rotenone induced Parkinsonism in wistar rats
Objective: The present study was aimed to explore the synergistic neuroprotective effect of combination of natural phenolic compound, i. e., chlorogenic acid, and butanol extract…Low doses of scopolamine exacerbates dementia among Drosophila with Parkinson’s disease pathophysiology
Objective: To assess the non-inducing doses of scopolamine (SCL) on the memory function of Drosophila previously induced with Parkinson's disease phenotype. Background: A large body…The role of lipid metabolism in mouse models of Parkinson’s disease
Objective: To investigate the role of lipid metabolism and the effect of blocking carnitine palmitoyl-transferase 1 (CPT1) in toxic and genetically mouse models of Parkinson’s…The Role of Environmental Toxins (Rotenone) in Parkinson’s Disease
Objective: Learn the role of environmental toxins - rotenone in development of Parkinson's disease Background: Rotenone is a powerful pesticide. It is also a lipophilic…Exposed-Only Analysis of Gene-Pesticide Interaction in Parkinson’s Disease (PD)
Objective: Assess gene-pesticide associations with PD using an exposed-only design in a highly exposed cohort. Background: Pesticide use is associated with an increased risk of…Curcumin improves cognitive function in rotenone-induced rat model of Parkinson’s disease (PD)
Objective: In this study, we aimed to investigate the neuroprotective effect of curcumin against rotenone-induced memory impairments in rat PD model. Background: In PD, oxidative…Alpha-synuclein oligomer and rotenone treatments injury the dopaminergic neuron via inhibiting the expression of gene SEMA6D
Objective: To investigate the expression of Semaphorin6D (SEMA6D) and its interaction with Plexin-A1 in cellular Parkinson's disease(PD) models induced by α-synuclein and rotenone. Background: In…Neuromodulatory propensity of Ginko biloba to offset rotenone induced behaviour and biochemical alteration
Objective: The aim of present study was to evaluate neuromodulatory propensity of Gingko Biloba in rotenone induced Mice Model of Parkinson Disease in terms of…Neuroprotective effects of coffee ingredients against rotenone-induced neurodegeneration in parkinsonian model
Objective: In this study, we examined neuroprotective effects of coffee ingredients, caffeic acid (CA) and chlorogenic acid (CGA), against rotenone-induced neurodegeneration using primary cultured cells…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.