Alleviation of Parkinson’s and Associated Depression using Silymarin in Rotenone induced Mice Model of Parkinson’s Disease
Objective: The present study was undertaken in order find out the possible neuroprotective and antidepressant potential of Silymarin. The neuroprotective and antidepressant potential was evaluated…Limitations of Curcumin as a Therapeutic Agent in Rotenone Induced Dopaminergic Neurodegeneration: Insights from Drosophila Model of Parkinson’s Disease
Objective: To understand the efficacy of curcumin in rotenone induced Drosophila model of Parkinson’s disease. Background: Parkinson’s disease (PD) is the second most common neurodegenerative…High repressive activity of olive extracts on the cell line model of Parkinson disease against ROS induction
Objective: Neurodegenerative diseases including Parkinson’s disease (PD) mostly accompany with induction of high ROS in neuronal cells. It is believed that unusual level of ROS…Quercetin administration abrogates the Parkinson’s disease (PD)-like motor and non-motor symptoms and attenuates the behavioral, neurochemical and biochemical deficits induced by rotenone toxicity in rats
Objective: The present study was carried out to investigate the preventive and therapeutic effects of quercetin (a flavonol) against rotenone-induced neurotoxicity. Background: Rotenone (pesticide) induced…Chlorogenic acid and Trianthema portulacastrum combinational therapy mitigates rotenone induced Parkinsonism in wistar rats
Objective: The present study was aimed to explore the synergistic neuroprotective effect of combination of natural phenolic compound, i. e., chlorogenic acid, and butanol extract…Low doses of scopolamine exacerbates dementia among Drosophila with Parkinson’s disease pathophysiology
Objective: To assess the non-inducing doses of scopolamine (SCL) on the memory function of Drosophila previously induced with Parkinson's disease phenotype. Background: A large body…Neuromodulatory propensity of Ginko biloba to offset rotenone induced behaviour and biochemical alteration
Objective: The aim of present study was to evaluate neuromodulatory propensity of Gingko Biloba in rotenone induced Mice Model of Parkinson Disease in terms of…Neuroprotective effects of coffee ingredients against rotenone-induced neurodegeneration in parkinsonian model
Objective: In this study, we examined neuroprotective effects of coffee ingredients, caffeic acid (CA) and chlorogenic acid (CGA), against rotenone-induced neurodegeneration using primary cultured cells…Neuroprotective Effects of A Combination of Curcumin and Mucuna Prurience in Rotenone Induced Mice Model of Parkinson’s Disease
Objective: In the current study we have evaluated possible synergistic neuroprotective effect of two Poly-Phenols from Curcumin and Mucuna Prurience. The combine treatment of Curcumin…Inhibition of HDAC4 attenuates rotenone-induced abnormal increase of α-synuclein levels and affects autophagic flux in human dopaminergic SH-SY5Y cells
Objective: To explore the effects of selective inhibition of HDAC4, on levels of α-syn and autophagy-related proteins in PD. To discuss the mechanism for the…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.