DIRECT DBS: A prospective, multi-center clinical trial with blinding for a directional DBS lead
Objective: DIRECT DBS is an exploratory study which will investigate the effects of subthalamic deep brain stimulation (DBS) using directional DBS leads with current steering…Whole body vibration therapy with exercise enhances motor function and improves quality of life in Parkinson’s disease
Objective: To evaluate the short term effects of whole body vibration and exercise in patients with Parkinson's disease on overall quality of life, gait, tremor,…Quantification of tremor and rigidity during deep brain stimulation surgery for Parkison’s disease
Objective: The aim of this study is to validate practical and objective measures to assess changes in rigidity and tremor due to micro-lesion effects and…Motor rigidity selectively associates with impaired odor identification in Parkinson’s disease
Objective: To investigate the relationship between impairments of the cardinal motor symptoms and odor identification deficits in Parkinson's disease (PD). Background: Although hyposmia has been…Clinical and MRI-characteristics of drug-induced parkinsonism in Uzbekistan
Objective: To establish clinical and MRI morphometric differences between Parkinson's disease (PD) and Drug-induced parkinsonism (DP). Background: DP – is the most known side effect…Influence of motor manifestation and onset’s side on the spectrum of non-motor symptoms in patients with Parkinson’s disease
Objective: To analyze Parkinson's disease (PD) motor manifestation and onset's side influence on the spectrum of non-motor symptoms (NMS). Background: Possibly the onset's side and…A case of PD with non -motor symptoms onset
Objective: PD is a degenerative disorder of the central nervous system mainly affecting the motor system. In addition to motor symptoms, PD can impair other…The initial motor symptom of Parkinson’s disease in relation to age at onset and gender: A Sri Lankan perspective
Objective: To investigate whether the predominant initial PD motor symptom is associated with gender or age of onset of PD in Sri Lanka. Background: Studies…Efficacy and safety of a L-dopa delivery and monitoring medical device
Objective: The objective of this study is to evaluate algorithms in a medical device for l-dopa delivery and monitoring. This wearable medical device will measure…FBOX07 mutation with juvenile parkinsonism and behavioral disorders
Objective: FBX07 (PARK15) mutations cause juvenile parkinsonism with autosomal ressesive inheritance. Juvenile parkinsonism, pyramidal tract signs and atypical symptoms such as dystonia, chorea, behavioral disturbances,…
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