Treatment of dopaminergic augmented RLS with Ecopipam, A D1 specific antagonist: an exploratory placebo controlled cross-over trial
Objective: To establish initial safety and preliminary efficacy of ecopipam, a D1 specific antagonist in patients currently taking dopamine agonist and demonstrating augmentation. Background: Dopamine…Botulinum toxin in Restless Leg Syndrome – A Randomized Double-Blind Placebo-Controlled Study
Objective: To study the efficacy of incobotulinumtoxin A (IncoA) in relieving the symptoms of restless legs syndrome (RLS) Background: RLS is a common movement disorder…The Role of Clinical Outcome Assessment (COA) Data in the Drug Approval Process of Medicines for the Treatment of Restless Legs Syndrome (RLS): A Review of the Labels of Medicines Approved by the FDA and the EMA
Objective: The objectives of this study were 1) to identify the medicines approved for the treatment of restless legs syndrome (RLS) by the Food and…Duodopa for the treatment of severe restless legs syndrome
Objective: To describe the outcome of a patient with restless legs syndrome (RLS) and augmentation phenomena that was treated with Duodopa in continuous infusion. Background:…Systematic review and meta-analysis of randomized controlled trials to evaluate placebo response in restless legs syndrome
Objective: To quantify the magnitude of the placebo response in restless legs syndrome (RLS). Background: RLS is a common sensorimotor disorder characterized by an urge…Clinical characterization of pramipexole induced edema in Parkinson’s disease (PD). Is it always the best option discontinue the treatment?
Objective: Report a patient with PD treated with irregular doses of pramipexole and extensive chronic edema in lower extremities after 8 years of treatment, taking…