Next-generation sequencing of plasma-associated extracellular vesicle miRNAs as potential biomarkers for Parkinson’s disease and its prodromal stage
Objective: This study aimed to identify subsets of plasma EV-associated miRNAs with diagnostic potential for PD and iRBD, the prodromal stage of PD. Background: Parkinson’s…An Eyes-Open/Closed Manipulation Reveals Disrupted Default Mode Network Connectivity in Parkinson’s Disease and REM Sleep Behavior Disorder
Objective: To spatially localize disruptions in default mode network connectivity in prodromal and diagnosed Parkinson’s disease relative to controls. Background: Previously our research team reported…Dynamic functional connectivity changes in Parkinson’s disease patients with REM sleep behavior disorder
Objective: Our aim was to explore dynamic network connection changes in PD patients with RBD. Background: Rapid eye movement (REM) sleep behavior disorder (RBD) is…VMAT2 availability in Parkinson’s Disease with Rapid Eye Movement Sleep Behaviour Disorder
Objective: To use [11C]DTBZ PET imaging to explore vesicular monoamine transporter 2 (VMAT2) availability in Parkinson’s disease (PD) with and without rapid eye movement sleep…Abnormalities of vestibular-evoked myogenic potentials are associated with REM sleep without atonia in early Parkinson’s disease and idiopathic REM sleep behavior disorder
Objective: To explore the brainstem lesion reflected by means of vestibular-evoked myogenic potentials(VEMPs) and its association with REM sleep without atonia(RSWA) and other clinical assessments…CLINICAL CHARACTERISTICS OF PARKINSON’S DISEASE WITH PROBABLE RAPID EYE MOVEMENT SLEEP BEHAVIOR DISORDER
Objective: To determine the clinical characteristics of Parkinson’s Disease (PD) patients with probable Rapid eye movement sleep behavior disorder (pRBD) compared to PD patients without…Impulse control disorders in idiopathic REM sleep behaviour disorder and drug-naive Parkinson’s disease
Objective: To compare the frequency of impulse control disorders and compulsive behaviours (ICBs) in patients with iRBD and drug-naive PD, and to identify risk factors…Relationship between REM sleep without atonia and sleep architecture in multiple system atrophy
Objective: To investigate whether REM sleep without atonia (RWA) is associated with sleep architecture in patients with multiple system atrophy (MSA). Background: In MSA patients,…Improving estimation of Parkinson’s disease risk – enhancing the PREDICT-PD algorithm
Objective: To develop and test an enhanced algorithm for the prediction of Parkinson’s disease (PD) risk. Background: The PREDICT-PD algorithm estimates risk of PD using…Development and validation of a profile of peripheral immune biomarkers for Parkinson’s disease: A multicenter, retrospective study
Objective: This multicenter study was designed to investigate the association between multiple peripheral immune biomarkers and the risk of Parkinson’s disease (PD). Background: Several studies…
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