Affected tongue movements in idiopathic REM sleep behavior disorder
Objective: In Parkinson’s disease (PD), recognition of speech deviations often follows clinical diagnosis. But what if speech is a prodromal biomarker in PD? The study…Sleep stability, arousals and cycle structure in alfa-synucleinopathies: a comparative study between isolated REM sleep behaviour disorder (iRBD), Parkinson’s Disease (PD) and Dementia with Lewy Bodies (DLB)
Objective: To compare sleep stability, arousals and sleep cycle structure between two sets of diagnosis: iRBD vs PD vs DLB; patients with RBD (RBD+) vs…Feasibility of artificial intelligence in predicting early phenotype conversion of REM Sleep Behavior Disorder
Objective: The goal of this study was to investigate the feasibility of deep learning in the prediction of disease conversion in RBD patients. Background: Rapid…Design of a prodromal screening study for subtypes in Parkinson’s Disease
Objective: To follow-up prodromal Parkinson’s Disease (PD) subtypes in a longitudinal cohort study, validating new biomarkers and ethical guidelines for early detection of PD. Background:…Relationship between brain bioelectrical activity during REM/NREM sleep, grey matter changes and visual disorders in patients with RBD in Parkinson’s disease
Objective: To investigate the brain bioelectric activity during REM/NREM sleep and determine the relationship with visual impairment and structural brain alteration in non-demented PD patients…The Functional Impact of REM Sleep Behavior Disorder in Parkinson’s Disease with Mild Cognitive Impairment
Objective: This study examines whether severity and the functional impact of cognitive decline in Parkinson’s disease mild cognitive impairment (PD MCI) participants differ between those…Next-generation sequencing of plasma-associated extracellular vesicle miRNAs as potential biomarkers for Parkinson’s disease and its prodromal stage
Objective: This study aimed to identify subsets of plasma EV-associated miRNAs with diagnostic potential for PD and iRBD, the prodromal stage of PD. Background: Parkinson’s…An Eyes-Open/Closed Manipulation Reveals Disrupted Default Mode Network Connectivity in Parkinson’s Disease and REM Sleep Behavior Disorder
Objective: To spatially localize disruptions in default mode network connectivity in prodromal and diagnosed Parkinson’s disease relative to controls. Background: Previously our research team reported…Dynamic functional connectivity changes in Parkinson’s disease patients with REM sleep behavior disorder
Objective: Our aim was to explore dynamic network connection changes in PD patients with RBD. Background: Rapid eye movement (REM) sleep behavior disorder (RBD) is…VMAT2 availability in Parkinson’s Disease with Rapid Eye Movement Sleep Behaviour Disorder
Objective: To use [11C]DTBZ PET imaging to explore vesicular monoamine transporter 2 (VMAT2) availability in Parkinson’s disease (PD) with and without rapid eye movement sleep…
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