Eye tracking paradigm to identify disease-specific behavioral biomarkers in neurodegeneration
Objective: Rapid-eye movement (REM) sleep behavior disorder (RBD) has been identified as the most specific and common prodromal stages of α-synucleinopathies (αSYN) such as Parkinson's…Impaired structural connectivity in Parkinson’s disease with probable RBD
Objective: To characterize structural connectivity through whole-brain network-based statistics and graph theory implementation in treated Parkinson’s disease (PD) patients with probable REM sleep behavior disorder…Increased free water in the putamen in idiopathic REM sleep behaviour disorder
Objective: This study aimed to evaluate the free water in the dorsoposterior putamen of idiopathic REM sleep behaviour disorder (iRBD) patients, which is considered a…An Algorithmic Approach to Assessing Cognitive Functioning in Individuals with REM Sleep Behavior Disorder
Objective: To apply an algorithmic approach to interpretation of cognitive data to assess cognitive impairment in RBD participants. Background: Cognitive changes in emerging neurodegenerative disease…Impact of globus pallidus interna deep brain stimulation on REM sleep behavior disorder in Parkinson’s disease
Objective: The aim of this study was to determine if there is an improvement in rapid eye movement (REM) sleep behavior disorder (RBD) for patients…Phenotypic presentation of essential tremor patients with Rapid eye movement disorder
Objective: To describe the prevalence of rapid eye movement disorder (RBD) among essential tremor (ET) patients and its correlates in terms of associated motor and…Gray matter volume of proposed brain-first and body-first Parkinson’s disease subtypes
Objective: The aim of this study was to test if markers of the brain-first Parkinson’s disease (PD) subtype are associated with a greater or more…Preliminary results on the cognitive profile in prodromal Parkinson’s disease – a prospective study
Objective: This study aims to investigate the cognitive profile in people with REM-sleep behavior disorder (RBD) and hyposmia, in a prodromal Parkinson’s disease (PD) cohort.…The benefit of exclusive nocturnal administration of a levodopa-carbidopa intestinal infusion for severe refractory sleep behavior disorder in Parkinson’s disease
Objective: Treatment by continuous diurnal intestinal infusion of levodopa is effective in improving sleep quality in Parkinson's disease (PD), but its use exclusively at night…Anti-α-synuclein antibody 5G4 differentiates idiopathic REM Sleep Behavior Disorder patients from healthy controls in skin biopsies
Objective: The aim of our study was to assess α-synuclein (α-syn) staining using the 5G4 antibody in skin samples of patients with idiopathic REM Sleep…
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