“Brain-first” vs. “body-first” Parkinson’s disease is determined by RBD-status – a multi-modality imaging study
Objective: In a multi-modality imaging study, we test the hypothesis that Parkinson’s disease (PD) can be divided into two strikingly distinct phenotypes: (1) PD patients,…Efficacy and Safety of the 5-Hydroxytryptophan on REM Sleep Behavior Disorder in Parkinson’s Disease.
Objective: To evaluate the efficacy of the 5-HTP on RBD status in patients with Parkinson's disease (PD). Background: REM sleep behavior disorder (RBD) is reported…Potential treatment considerations for refractory REM behavior disorder
Objective: A meta-analysis of alternative treatment therapies for refractory REM behavior disorder. Background: Parkinson’s disease is a neurodegenerative syndrome that affects motor and non-motor functions.…Sleep Aspects on Video-Polysomnography in P.A53T SNCA Mutation Carriers
Objective: To determine whether REM sleep behavior disorder (RBD) and other sleep abnormalities occur in carriers of the p.A53T alpha-synuclein gene (SNCA) mutation, the prototypical…Preliminary evidence for an altered relationship between uric acid levels and resting state functional connectivity in REM sleep behavior disorder
Objective: To determine the relationship between uric acid (UA) levels and functional connectivity in REM sleep behavior disorder (RBD) compared to controls. Background: UA levels…Diminished fMRI global signal differences between eyes closed and eyes open resting state in RBD and PD
Objective: test whether patients with Parkinson’s diseases (PD) and REM sleep behavior disorder (RBD) exhibit diminished state-related changes in their resting state fMRI global signal.…Exploring the neural correlates of gait asymmetry in idiopathic REM Sleep Behaviour Disorder
Objective: Given the typical asymmetric onset of motor symptoms in PD, the current study sought to investigate whether patients with iRBD show evidence of asymmetric…In vivo staging of pathology in REM sleep behaviour disorder
Objective: To study the level of dysfunction in the peripheral and central nervous system in idiopathic REM sleep behaviour disorder (iRBD) patients. Background: α-synuclein (α-syn)…Efficacy of prolonged release melatonin for REM sleep behaviour disorder in Parkinson’s disease: A double blind, randomised, placebo-controlled trial
Objective: Test the efficacy of prolonged-released melatonin for REM sleep behaviour disorder (RBD) in Parkinson’s disease (PD). Background: Half of all PD patients experience RBD…Temporal evolution of biomarkers from healthy ageing, isolated REM sleep behavior to early Parkinson’s disease
Objective: To study the temporal evolution of biomarkers of various modalities in healthy ageing controls (HC), the prodromal condition of isolated REM sleep behavior disorder…
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