Parkinson Progression Marker Initiative 2.0 – New Science/New Cohorts
Objective: The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes,…Relationship between REM sleep without atonia and sleep architecture in multiple system atrophy
Objective: To investigate whether REM sleep without atonia (RWA) is associated with sleep architecture in patients with multiple system atrophy (MSA). Background: In MSA patients,…Improving estimation of Parkinson’s disease risk – enhancing the PREDICT-PD algorithm
Objective: To develop and test an enhanced algorithm for the prediction of Parkinson’s disease (PD) risk. Background: The PREDICT-PD algorithm estimates risk of PD using…Development and validation of a profile of peripheral immune biomarkers for Parkinson’s disease: A multicenter, retrospective study
Objective: This multicenter study was designed to investigate the association between multiple peripheral immune biomarkers and the risk of Parkinson’s disease (PD). Background: Several studies…Study on the clinical features of Parkinson’s disease with probable rapid eye movement sleep behavior disorder
Objective: To investigate the clinical features and associated factors of Parkinson's disease (PD) patients with probable rapid eye movement sleep behavior disorder (PD-pRBD) Background: RBD…SNCA hypomethylation in rapid eye movement sleep behavior disorder is a potential biomarker for Parkinson’s disease
Objective: We aimed to explore whether there were different distributions of α-synuclein at a genetic and/or protein level in patients with iRBD. Background: α-Synuclein has been related to…White matter abnormalities and its relation to cognitive impairment in isolated Rapid Eye Movement sleep behavior disorder
Objective: To study white matter (WM) abnormalities and global cortical atrophy in isolated rapid eye movement sleep behavior disorder (IRBD) patients and its relation to cognitive…The short- and long-term outcomes of STN DBS in PD patients with or without RBD
Objective: We aimed to assess the short- and long-term outcomes of bilateral subthalamic (STN) deep brain stimulation (DBS) including the motor performance and quality of…In the shadow of Parkinson disease: what to tell patients with REM sleep behavior disorder?
Objective: To describe challenges to patient counseling in REM sleep behavior disorder (RBD). Background: RBD is a significant risk factor for development of Parkinson disease…The influence of gender, associated neurological disorder and motive for polysomnography (PSG) in the manifestations of REM sleep behaviour disorder (RBD)
Objective: To access the interrelation and relative influence of gender, associated neurological disorder and context of referral to PSG on the manifestations of (RBD). Background:…
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