Neuropathological correlates of psychiatric disorders in PD
Objective: To test the hypothesis that neuropsychiatric symptoms (NPS) in PD are associated with histopathologically confirmed neuronal loss and gliosis (NLG) in the locus coeruleus…Pimavanserin Combined With Anti-Dementia Medications for Parkinson Disease Psychosis
Objective: To evaluate the differential antipsychotic effect of pimavanserin, a selective serotonin (5-HT2A) receptor inverse agonist, for Parkinson’s disease psychosis with and without concomitant anti-dementia…Suicide attempts, suicidal and death ideation in Parkinson’s disease
Objective: The objective of this study was to assess the correlates of suicidal and death ideation and suicide attempts in patients with parkinson’s disease. Background:…Patients with Parkinson’s disease and psychosis have altered structural connectivity of the executive and visual networks
Objective: To analyze the integrity of visual and executive network of patients with Parkinson’s disease (PD) with psychosis (PD-P) and those without psychosis (PD-NP) and…Examining Parkinson’s disease psychosis treatment outcomes in the real world: The insyte observational study
Objective: The INSYTE Study–seeks to gain a better understanding of the management of PDP. INSYTE will describe the relative safety and effectiveness of various antipsychotic…Evaluation of Parkinson’s Disease Psychosis Requires Structured Questioning of Patients and Caregivers
Objective: To determine the relationship between the patient and caregiver experience of the psychotic features of Parkinson's disease psychosis (PDP) reported to call center healthcare…Patient Experience of Parkinson’s Disease Psychosis Management
Objective: To understand the experience and management of Parkinson’s disease psychosis (PDP). Background: PDP is a troubling non-motor symptom of Parkinson’s disease. Clinical approaches to…Patterns of Long-Term Custodial Care in Parkinson Disease Psychosis
Objective: Parkinson Disease (PD) progression is frequently associated with development of psychosis (P), leading to significant morbidity, caregiver distress, and other consequences. Although PDP often…Highly-selective blockade of 5-HT2A receptors with EMD-281,014 reduces the severity of L-DOPA-induced psychosis and dyskinesia in the MPTP-lesioned marmoset model of Parkinson’s disease
Objective: To investigate the effect of the highly-selective serotonin 2A (5-HT2A) receptor EMD-281,014 on L-3,4-dihydroxyphenylalanine (L-DOPA)-induced psychosis-like behaviours (PLBs) and dyskinesia in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-lesioned…Post-Deep Brain Stimulation Psychosis in Parkinson’s Disease: A Meta-analysis
Objective: This systematic review and meta-analysis was designed to evaluate risk factors and correlates of psychosis in PD after DBS surgery. Background: Deep brain stimulation…
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