COMBINED CSF α-SYN RT-QuIC, CSF NFL AND MIDBRAIN-PONS PLANIMETRY IN DEGENERATIVE PARKINSONISMS: FROM BEDSIDE TO BENCH, AND BACK AGAIN
Objective: (1) to assess the combined diagnostic ability of CSF NFL, CSF RT-QuIC α-SYN and midbrain/pons MRI measures in degenerative parkinsonisms; (2) to interpret results…Cognitive and Psychiatric Correlates of Fear of Falling in Progressive Supranuclear Palsy and Multiple System Atrophy
Objective: To evaluate the clinical correlates of fear of falling (FoF) in patients with Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA) Background: FoF…Probable Four-repeat tauopathy criteria in Corticobasal Syndrome: diagnostic accuracy, clinical features and imaging biomarkers
Objective: To compare the “probable four-repeat (4R)-tauopathy” criteria[1] with the clinical research(cr) criteria for corticobasal degeneration (CBD) [2] regarding diagnostic accuracy to predict a negative…Effects of venlafaxine on neuropsychiatric and motor symptoms in patients with progressive supranuclear palsy
Objective: This prospective, ongoing, interventional trial is related to the ProPSP registry and aims to characterize the effects of venlafaxine, a serotonin-norepinephrine reuptake inhibitor, on…Variability in Age of Onset, Age of Diagnosis and Age of Death for Progressive Supranuclear Palsy Patients Among Three Racial Groups in Hawai`i
Objective: To examine if differences in age of symptom onset, age of diagnosis, age of death, and number of years lived after diagnosis exist for…Explorative study of analysis of the role of NFL and IGF1 in Indian patients with PSP and its clinical correlation.
Objective: In this prospective cross sectional case control study, we have investigated the relationship of serum levels of Neurofilament light chain and Insulin like growth…Automated Midbrain-Pons Ratio using Artificial Intelligence Differentiates PSP from other Atypical Parkinsonian Disorders
Objective: Our primary goal was to implement an automated measure of the midbrain to pons ratio (MPR) using an artificial intelligence method. Our second objective…A retrospective review of clinical features of Progressive Supranuclear Palsy (PSP) in a movement disorders clinic
Objective: Understanding the common clinical features of PSP. Background: PSP is a relatively rare progressive neurodegenerative disease, which can often be difficult to distinguish from…Backward Fall Protection Garment for patients of PSP and other Parkinsonian Syndromes.
Objective: To create a sensor controlled wearable system with an inflatable collar that offers protection against head, spine and shoulder girdle injuries in case of…Neuroimaging associations to gait impairments in progressive supranuclear palsy
Objective: The aim of this study was to determine how multimodal imaging biomarkers were related to abnormalities in three-dimensional motion-based gait and balance measurements in…
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