Gait initiation in patients with Progressive Supranuclear Palsy: a biomechanical and FDG-PET study
Objective: To define the brain metabolic abnormalities related to gait initiation (GI) failure in subjects with Progressive Supranuclear Palsy (PSP). Background: PSP is an atypical…Glucocerebrosidase activity and atypical parkinsonism: a multi-centre exploratory study
Objective: We aimed to determine the frequency of Glucocerebrosidase (GBA) deficiency (subclinical Gaucher's Disease type 1, GD1) in patients with atypical parkinsonism (AP) with features…Long and short survival in Parkinson syndrome: pathology and genetics are key prognostic factors
Objective: To study the clinical, pathological and genetic profile of Parkinson syndrome (PS) cases that have > 20 years survival (long survival, or LS) compared…Is brain perfusion a differentiating factor between Parkinson’s Disease (PD) and Progressive Supranuclear Palsy – Parkinsonism Predominant (PSP-P)?
Objective: Parkinson’s Disease – Postural Instability Gait Disorder (PD-PIGD) and Progressive Supranuclear Palsy – Parkinsonism Predominant (PSP-P) are entities affected by difficulties in differentiation in…Serum neurofilament light chain differentiates early Parkinson’s disease from progressive supranuclear palsy-parkinsonism
Objective: To assess the value of serum neurofilament light chain (NFL) levels in differentiating parkinsonian syndromes. Background: The diagnosis of Parkinson’s disease (PD) mostly relies…Cognitive Differences Between Men and Women with Progressive Supranuclear Palsy
Objective: (1) To evaluate the cognitive differences between men and women with progressive supranuclear palsy (PSP) and (2) to investigate whether sex has an effect…Inertial sensor-based kinematics in the differential diagnosis of Parkinson’s disease and atypical parkinsonisms
Objective: Assess the role of inertial sensors in the phenotyping and differential diagnosis of Parkinson’s Disease vs. Atypical Parkinsonisms Background: Wearable devices have been used…Midbrain/pons area ratio and clinical features predict the prognosis of Progressive Supranuclear Palsy
Objective: This retrospective study aims to characterize the natural history of PSP and to find predictors of shorter survival and faster decline of activity of…Correlations between amantadine usage, gait, and cognition in PSP: a post hoc analysis of the davunetide trial
Objective: Amantadine anecdotally improves gait and balance in PSP, potentially by increasing alertness, but there are no definitive data to support this observation. We investigated…The Impact of Progressive Supranuclear Palsy (PSP) Disease Severity on Caregivers
Objective: To quantify the impact of varying severity levels on caregivers’ burden and health-related quality of life (HRQoL). Background: PSP is a progressive disease. Patients…
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