Differential Diagnosis of Parkinsonism with 18F-FP-CIT PET using a Self-supervised Deep Learning Model
Objective: To develop a self-supervised deep learning model using 18F-FP-CIT PET images from patients with Parkinsonism and to evaluate the model’s performance in the differential…Early Dementia with Lewy Bodies and Parkinson’s Disease with RBD: two faces of the same coin?
Objective: To describe clinical and imaging differences in de novo PD with and without REM sleep Behaviour Disorder (dnPDRBD – de novo PD) and de…Investigating the Use of 18F-DOPA PET/CT to Improve Diagnosis and Clinical Management of Parkinson’s Disease in South Australian Movement Disorder Clinics.
Objective: Evaluate the impact of 18F-DOPA PET/CT on clinical management for Parkinsonism. Background: Parkinson’s Disease affects >100,000 people in Australia with an economic burden of…Brainstem Monoaminergic Degeneration, Cognition, and Autonomic Symptom Progression in Early Parkinson’s Disease
Objective: In this study, we aimed to investigate the association between brainstem monoaminergic nuclear degeneration, particularly the serotonergic raphe and noradrenergic locus coeruleus, and cognitive…Cerebral metabolic network in PLA2G6-associated parkinsonism
Objective: To characterize the cerebral metabolic network in PLA2G6-associated parkinsonism (PLA2G6-P). Background: PLA2G6-associated neurodegeneration is known as a continuum of phenotypes. Patients with late-onset PLA2G6-associated…Automated VMAT2 [18F]AV-133 PET analysis in Parkinson’s disease
Objective: To evaluate a fully automated image analysis pipeline to process vesicular monoamine transporters type 2 (VMAT2) [18F]AV-133 tracer positron emission tomography (PET) images, by…Altered brain energetics in Parkinson’s Disease: a multimodal neuroimaging study
Objective: To investigate patterns of altered brain energetics in Parkinson’s disease (PD). Background: Alterations in mitochondrial function, related to brain energetics, may play an important…Relevance of amyloid deposition for REM sleep behavior disorder in Parkinson’s disease
Objective: In this study, we aimed to investigate the relationship between regional [18F]florbetaben PET binding to amyloid-β (Aβ) and REM sleep behavior disorder (RBD) in…Progression of striatocortical dysfunction in Parkinson’s disease: a longitudinal combined PET and fMRI study
Objective: To investigate the longitudinal progression of striatal dopaminergic dysfunction and its consequences on functional connectivity (FC) networks and clinical progression in Parkinson's disease (PD)…Cerebral Topography of [11C]-Flumazenil GABAA Receptor Expression in Parkinson’s Disease Fallers and Freezers
Objective: To examine the cerebral topography of GABAA Receptor Expression in Parkinson’s Disease (PD) Fallers and Freezers. Background: Episodic mobility disturbances, like falls and freezing…
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