Multimodal imaging assessment of nigrostriatal pathway in Parkinson’s disease using 11C-PE2I PET and neuromelanin-sensitive MR
Objective: To evaluate the nigrostratal pathway with multimodal assessment using striatal 11C-PE2I PET and nigral Neuromelanin-sensitive MR in Parkinson's disease. Background: The main pathological features…Striatal PDE10 expression in Parkinson’s disease (PD) and healthy controls using [18F]MNI-659 PET imaging
Objective: To evaluate the feasibility of [18F]MNI-659 PET, a striatal PDE10A imaging tracer, as a imaging biomarker in PD. Background: PDE10 is highly and specifically…Comparison of DAT and DOPA PET tracer for assessing severity and progression in patients with Parkinson’s disease
Objective: The aims of this study were to quantify striatal uptake of 18F-DOPA and 11C-PE2I in the same group of PD patients, to assess the…Persistent drug-induced parkinsonism with normal dopamine transporter imaging
Objective: We investigated whether patients with persistent drug-induced parkinsonism (DIP) showing visually normal dopamine transporter (DAT) imaging had minimal changes in striatal DAT activity using…Cerebellar GABA-A receptor activity is inversely correlated with gait speed in Parkinson’s disease
Objective: To investigate the relationship between regional cerebral expression of benzodiazepine receptors and gait speed in Parkinson's disease (PD). Background: Flumazenil is a short-acting intravenously…Frontal dysfunction in Tourette syndrome: A PET-FDG study
Objective: Our objective was study the metabolism of brain in a group of patients with Tourette´s Syndrome. Background: The pathophysiology and anatomical basis of Tourette…Dopaminergic and metabolic network activities in onset-related subtypes of Parkinson’s disease: A dual-tracer positron emission tomography study
Objective: The current study investigated the differences of dopaminergic and metabolic patterns between the young-onset subtype of Parkinson's disease (YOPD) and the late-onset subtype (LOPD)…Phenotypes in Essential Tremor: Gait analysis and imaging study
Objective: If essential tremor (ET) is the most common movement disorder in adults, its pathophysiology remains poorly understood and few data are available as for…Novel PET Tracers of alpha-synuclein for the diagnosis of Parkinson’s disease
Objective: The aim of our project is to develop small molecular weight compounds (Morphomers™) which bind selectively to alpha-synuclein (aSyn) aggregates, in order to generate…Substantia nigra α4β2 nicotinic cholinergic receptor expression correlates with tremor in Parkinson’s disease
Objective: To investigate the relationship between tremor and α4β2 nicotinic cholinergic receptor (nAChR) expression in brain regions associated with tremor in Parkinson's disease (PD), including…
Abstracts from the International Congress of Parkinson’s and Movement Disorders.