Frontal dysfunction in Tourette syndrome: A PET-FDG study
Objective: Our objective was study the metabolism of brain in a group of patients with Tourette´s Syndrome. Background: The pathophysiology and anatomical basis of Tourette…Dopaminergic and metabolic network activities in onset-related subtypes of Parkinson’s disease: A dual-tracer positron emission tomography study
Objective: The current study investigated the differences of dopaminergic and metabolic patterns between the young-onset subtype of Parkinson's disease (YOPD) and the late-onset subtype (LOPD)…Phenotypes in Essential Tremor: Gait analysis and imaging study
Objective: If essential tremor (ET) is the most common movement disorder in adults, its pathophysiology remains poorly understood and few data are available as for…Novel PET Tracers of alpha-synuclein for the diagnosis of Parkinson’s disease
Objective: The aim of our project is to develop small molecular weight compounds (Morphomers™) which bind selectively to alpha-synuclein (aSyn) aggregates, in order to generate…Substantia nigra α4β2 nicotinic cholinergic receptor expression correlates with tremor in Parkinson’s disease
Objective: To investigate the relationship between tremor and α4β2 nicotinic cholinergic receptor (nAChR) expression in brain regions associated with tremor in Parkinson's disease (PD), including…Targeted over-expression with AAV-mediated human α-synuclein in a rat model of Parkinson’s disease – Validation of novel fine motor functional effects
Objective: Targeted over-expression of human α-synuclein using viral-vector mediated gene delivery into the substantia nigra of rats and non-human primates has been reported to lead…Loss of extra-striatal phosphodiesterase 10A expression in early premanifest Huntington’s disease gene carriers
Objective: Using positron emission tomography (PET) with [11C]IMA107, we investigated the in vivo expression of PDE10A in extra-striatal regions in a cohort of 12 early…Metabolic brain changes related to specific cognitive impairment in non-demented Parkinson’s disease patients
Objective: To measure the expression of the Parkinson's disease related cognitive pattern (PDCP) in 18F-FDG-PET brain images of Parkinson's disease (PD) patients and healthy controls…Dysphagia in early stage Huntington’s disease (HD) – Pilot observations from a multimodal imaging study
Objective: To assess the central neural control of swallowing in HD patients with mild dysphagia using a multimodal imaging approach combining qualitative and quantitative swallowing…The evaluation of metabolic differences by using 18F-FDG-PET/CT in demented and non demented Idiophatic Parkinson’s disease patients
Objective: The objective of this study was to identify metabolic group differences between Idiopatic Parkinson's disease patients with dementia (PDD) and without dementia (PD), by…