MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Positron emission tomography(PET)"

  • 2017 International Congress

    Brain metabolic patterns in progressive supranuclear palsy phenotypes

    M.M. Carmona-Abellan, A. Fontes, E. Prieto, J. Arbizu, R. Luquin, M. Riverol (Pamplona, Spain)

    Objective: To describe changes in cerebral glucose metabolism in patients with different described clinical phenotypes of PSP and to correlate them with the clinical manifestations of the disease. Background:…
  • 2017 International Congress

    Voice Therapy Normalizes Feedforward and Feedback Networks of the Speech Motor System

    S. Narayana, C. Franklin, E. Peterson, D. Robin, P. Fox, L. Ramig (Memphis, TN, USA)

    Objective: The aim of the study was to isolate the specific effects of the training target of The Lee Silverman Voice Therapy (LSVT) in Parkinson’s…
  • 2017 International Congress

    The influence of LRRK2 mutations on cholinergic system in manifest and prodromal stage of Parkinson’s disease: a positron emission tomography study

    S. [email protected], D. Wile, J. Fu, J. Valerio, E. Shahinfard, S. McCormick, R. Mabrouk, N. Vafai, J. McKenzie, N. Neilson, A. Perez-Soriano, J. Arena, M. Cherkasova, J. Zhang, C. Zabetian, J. Aasly, Z. Wszolek, M. McKeown, V. Sossi, A. Stoessl (Beijing, China)

    Objective: To evaluate the effects of leucine-rich repeat kinase 2 (LRRK2) mutations on the central cholinergic system in both manifesting and non-manifesting carriers using PET…
  • 2017 International Congress

    Utility of THK-5351 tau-PET for differential diagnosis in patients with hypokinetic-rigid syndromes.

    G. Rohrer, S. Schönecker, M. Brendel, J. Havla, G. Höglinger, S. Lindner, C. Zach, F. Vettermann, C. Prix, G. Nübling, P. Bartenstein, K. Furukawa, A. Ishiki, N. Okamura, K. Bötzel, A. Rominger, J. Levin (Munich, Germany)

    Objective: The objective of our study is to investigate the  use of THK-5351 tau- PET-imaging as an additional tool for differential diagnosis in hypokinetic-rigid syndromes suggestive…
  • 2017 International Congress

    Functional role of the cerebellum in Parkinson’s disease : a PET-Study

    A. Riou, F. Le Jeune, J.-F. Houvenaghel, S. Drapier, M. Vérin, G. Robert (RENNES, France)

    Objective: The aim of this study is to confirm the hypothesis of a functional involvement of the cerebellum in Parkinson's disease according to a tri-compartmental…
  • 2017 International Congress

    Functional MAOB gene intron 13 polymorphism predicts putaminal dopamine turnover in de novo Parkinson’s disease

    M. Löhle, G. Mangone, M. Wolz, B. Beuthien-Baumann, L. Oehme, J. Hoff, J. Kotzerke, H. Reichmann, J.-C. Corvol, A. Storch (Rostock, Germany)

    Objective: To examine the effects of common functional polymorphisms in genes involved in dopamine metabolism on striatal dopamine turnover estimated as the inverse of the…
  • 2017 International Congress

    An evaluation of the diagnostic utility of radiological biomarkers in PSP

    J. Whitwell, G. Hoglinger, A. Antonini, Y. Bordelon, A. Boxer, C. Colosimo, R. Dodel, T. van Eimeren, L. Golbe, J. Kassubek, C. Kurz, I. Litvan, A. Pantelyat, G. Respondek, G. Rabinovici, J. Rowe, M. Stamelou, K. Josephs (Rochester, MN, USA)

    Objective: To critically evaluate the degree to which structural and molecular radiologic metrics fulfill criteria for diagnostic biomarkers of progressive supranuclear palsy (PSP). Background: PSP…
  • 2017 International Congress

    Interactions between amyloid-β and microglial activation in Parkinson’s disease

    C. Ghadery, Y. Koshimori, J. Kim, S. Coakeley, M. Harris, L. Christopher, P. Rusjan, A. Lang, S. Houle, A. Strafella (Toronto, ON, Canada)

    Objective: To evaluate the relationship between microglial activation and amyloid-β deposition in the brain using positron emission tomography (PET) in Parkinson’s disease (PD) with normal…
  • 2017 International Congress

    The role of phosphodiesterase 4 in sleep disturbances in Parkinson’s disease

    H. Wilson, G. Pagano, F. Niccolini, N. Muhlert, C. Coello, M. Mehta, G. Searle, R. Gunn, E. Rabiner, T. Foltynie, M. Politis (London, United Kingdom)

    Objective: We aimed to assess the association between phosphodiesterase 4 (PDE4) expression and sleep disturbances in vivo using combined multimodal magnetic resonance imaging (MRI) and…
  • 2017 International Congress

    Diagnostic utility of regional [18F]AV-1451 tau-PET measurements in PSP

    J. Whitwell, V. Lowe, N. Tosakulwong, S. Weigand, M. Senjem, C. Schwarz, A. Spychalla, R. Petersen, C. Jack, K. Josephs (Rochester, MN, USA)

    Objective: To determine the diagnostic utility of regional subcortical [18F]AV-1451 tau-PET measurements to differentiate progressive supranuclear palsy (PSP) from age-matched controls and Alzheimer’s dementia patients.…
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