Functional MAOB gene intron 13 polymorphism predicts putaminal dopamine turnover in de novo Parkinson’s disease
Objective: To examine the effects of common functional polymorphisms in genes involved in dopamine metabolism on striatal dopamine turnover estimated as the inverse of the…An evaluation of the diagnostic utility of radiological biomarkers in PSP
Objective: To critically evaluate the degree to which structural and molecular radiologic metrics fulfill criteria for diagnostic biomarkers of progressive supranuclear palsy (PSP). Background: PSP…Interactions between amyloid-β and microglial activation in Parkinson’s disease
Objective: To evaluate the relationship between microglial activation and amyloid-β deposition in the brain using positron emission tomography (PET) in Parkinson’s disease (PD) with normal…The role of phosphodiesterase 4 in sleep disturbances in Parkinson’s disease
Objective: We aimed to assess the association between phosphodiesterase 4 (PDE4) expression and sleep disturbances in vivo using combined multimodal magnetic resonance imaging (MRI) and…Diagnostic utility of regional [18F]AV-1451 tau-PET measurements in PSP
Objective: To determine the diagnostic utility of regional subcortical [18F]AV-1451 tau-PET measurements to differentiate progressive supranuclear palsy (PSP) from age-matched controls and Alzheimer’s dementia patients.…Extrapyramidal involvement in amyotrophic lateral sclerosis: results of a prospective population-based study
Objective: To assess frequency, clinical characteristics and functional neuroimaging correlates of parkinsonian signs in a population-based series of new-diagnosed amyotrophic lateral sclerosis (ALS) patients. Background:…[18F]-AV-1451 binding to neuromelanin in the substantia nigra in PD and PSP
Objective: This study was designed to investigate the binding of [18F]-AV-1451 to neuromelanin in parkinsonisms. Uptake in the substantia nigra of Parkinson’s disease (PD) and…Assessing cholinergic innervation in Parkinson’s disease using the PET imaging marker [18F]Fluoroethoxybenzovesamicol
Objective: To validate [18F]Fluoroethoxybenzovesamicol ([18F]FEOBV) imaging in healthy volunteers by dynamic scanning. The secondary objective of this study was to evaluate the differences in [18F]FEOBV binding…PET-MRI Imaging in Parkinson Dementia Complex of Guam: A Case Report
Objective: To describe the PET-MRI brain and DaTscan findings in a case of Parkinson Dementia Complex of Guam. Background: The indigenous Chamorro people of Guam…Hypometabolism in Orbitofrontal and Perirhinal Cortex is Associated with Impulse Control Disorder in Parkinson´s Disease
Objective: (i)To elucidate the metabolic correlates sub-serving the clinical expression of ICD in PD and (ii) to evaluate the association between the glucose metabolism and…
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