Automated Differential Diagnosis of Parkinsonian Syndromes Using FDG-PET Metabolic Brain Network Analysis
Objective: To discriminate among parkinsonian patients using an automated network analysis of FDG-PET brain images. Background: Clinical differentiating among parkinsonian syndromes: Parkinson’s disease (PD), multiple…A Florbetapir [F18] amyloid PET Imaging study in Parkinson’s disease Dementia (PDD): The influence of amyloid deposition on cognitive status and course of disease progression
Objective: To determine whether amyloid deposition, as assessed by PET imaging with the [18F]-Florbetapir, is related in patients with Parkinson Disease and Dementia (PDD) to…α4β2-nicotinic receptor availability in Parkinson’s disease MCI and healthy controls: A pilot imaging study using [18F]-XTRA PET
Objective: We aimed to show that a radiotracer with high affinity to cortical and hippocampal α4β2-nicotinic cholinergic receptors (1) would be reduced in regions associated…Dopaminergic dysfunction and abnormal metabolic network activity in REM sleep behavior disorder
Objective: This study is to investigate the correlations between the abnormalities in the distribution of striatal dopamine transporter (DAT) and the expression of Parkinson's disease…Combining PET imaging and blood metabolomics data to improve machine learning models for Parkinson’s disease diagnosis
Objective: To investigate whether the integration of PET imaging and metabolomics data can provide improved machine learning models for PD diagnosis. Background: The reliable diagnosis…Hypometabolism of the posterior parietal cortex in Parkinson’s disease with mild cognitive impairment predicts the conversion to dementia: 5-year longitudinal observations
Objective: To investigate the neuroimaging marker that predict the conversion of mild cognitive impairment (MCI) to dementia in Parkinson’s disease (PD) patients. Background: Patients with…The role of exposure to pesticides in the etiology of Parkinson’s disease: F-DOPA positron emission tomography study
Objective: To examine the pattern of ligand uptake on F-DOPA PET in patients with PD who were exposed or not exposed to pesticides and examine…Relation of asymmetry of dopamine depletion with motor or non-motor symptoms in patients with Parkinson’s disease: A pilot study
Objective: This study was aimed to investigate whether asymmetry of dopamine depletion through dopamine transporter (DAT) imaging is associated with motor or non-motor symptoms in…Specific Metabolic Brain Networks Associated with Parkinsonian and Cerebellar Variants of Multiple System Atrophy
Objective: To identify specific metabolic brain networks for parkinsonian (MSA-P) and cerebellar (MSA-C) variants of MSA. Background: MSA is associated with a disease-related metabolic brain network (MSARP)…Link between striatal dopamine uptake and cortical dysconnectivity in Parkinson’s disease
Objective: This study aims to explore pathways of reduced striatal dopamine synthesis in PD that may affect striato-cortical connectivity and implicate in altered glucose metabolism…
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