Mitochondrial Complex 1, Sigma 1 Receptor and Synaptic Vesicle protein 2A density in early de novo patients with Parkinson’s Disease: pilot PET data
Objective: In this study, we evaluated the density of Mitochondrial complex 1 (MC1), sigma 1 receptor (s1R) and Synaptic Vesicle protein 2A (SV2A) in early…Cerebrotendinous Xanthomatosis presenting Parkinsonism with bilateral iron accumulation in the basal ganglia
Objective: Cerebrontendinous xanthomatosis(CTX) is a treatable, autosomal recessive, lipid storage disorder disease. Herein, we present a case of CTX. It aims to refresh and improve…Decreased Cannabinoid Type 1 Receptor Density in Parkinson’s Disease: A [18F]FMPEP-d2 PET Study
Objective: To explore type 1 endocannabinoid receptor (CB1R) expression in subjects with Parkinson’s disease (PD) and healthy controls using [18F]FMPEP-d2 PET. Background: CB1Rs are expressed…Comparison of PDE10A and DAT expression as markers of disease burden in early Parkinson’s disease
Objective: We aimed to compare loss of PDE10A and DAT expression in patients with Parkinson’s disease. Background: Recent work has shown loss of PDE10A expression…Tongue Myokymia and Earache as a unique presentation Associated with Local Tongue Pathology: A Case Report and Review of Literature
Objective: Here we report a rare case of tongue carcinoma presenting by abnormal movements in the tongue in form of myokymia, and Earache. Background: Fasciculations…Classify Parkinson’s Disease with Mild Cognitive Impairment: Machine Learning Approach
Objective: To determine how multimodal neuroimaging data can contribute to the classification of Parkinson’s disease (PD) patients with mild cognitive impairment (MCI) from PD without…Progression of dopaminergic and serotonergic dysfunction related to motor and nonmotor manifestations in apathetic and non-apathetic parkinsonian patients: a 4-year longitudinal double-tracer PET study
Objective: To investigate the progression of dopaminergic and serotonergic dysfunction and their relation to motor and nonmotor impairment in parkinsonian patients with or without apathy,…Study of cardiac sympathetic denervation by 18F-FDOPA PET-CT Imaging in early Parkinson disease (EPD) and Atypical parkinsonian syndromes (APS)
Objective: To evaluate utility of l-3,4-dihydroxy-6-[18F] fluoro-phenylalanine (18F-FDOPA) PET-CT imaging for cardiac sympathetic denervation in conjunction with nigrostriatal imaging in patients with early Parkinson disease (EPD) and Atypical…Relative Preservation of Serotonergic Function Increases Response to Treatment in Early PD
Objective: To investigate interactions between the serotonergic and dopaminergic systems in early PD as related to (i) response to treatment and (ii) dopamine (DA) release,…Correlating subcortical structure and function in idiopathic Parkinson’s disease: A cross-sectional morphometric and [18F]-DOPA PET study
Objective: To investigate whether the local geometric changes in the subcortical structures of patients with idiopathic Parkinson’s disease correlate with dopaminergic terminal functional integrity within…
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