Premotor compensatory mechanisms in Parkinson’s disease with LRRK2-R1441H mutation
Objective: To investigate the time course of modifications in dopaminergic terminals during the premotor phase in LRRK2 genetically determined Parkinson’s disease (PD). Background: Increased dopamine…Graph theory analysis of dopamine D2 receptor network in Parkinson’s disease patients
Objective: The aim of this study was to explore a novel method of analyzing positron emission tomography (PET) data using graph theory analysis. To this…Neuroimaging of anxiety in Parkinson’s disease: a systematic review
Objective: The aim of this systematic review was 1) to identify the brain regions involved in anxiety in Parkinson's disease (PD) based on neuroimaging studies,…Impulse control disorder and ventral striatum dopamine D3 receptor availability in Parkinson’s disease
Objective: To investigate the relationship between ventral striatum D3 dopamine receptor availability and severity of impulse control disorder (ICD) in Parkinson’s disease (PD). Background: Reduced…In vivo imaging of presynaptic terminal loss in early Parkinson’s disease
Objective: To determine the magnitude and anatomical extent of presynaptic terminal damage in early Parkinson’s disease (PD) in vivo, we performed a PET study with…Levodopa-induced dyskinesias and substantia nigra dopamine D3 receptor availability in Parkinson’s disease
Objective: To investigate with PET and the radioligand [11C]PHNO whether levodopa-induced dyskinesias in Parkinson disease (PD) are associated with dopamine-D3 receptor (D3R) overexpression in substantia nigra…Correlation between location of active contacts and weight gain after subthalamic nucleus deep brain stimulation in Parkinson’s disease
Objective: Objective: The aim of this study was to evaluate the correlation between the location of active contacts and weight gain after subthalamic nucleus deep…Mechanisms of chronic neuroleptic-induced parkinsonism examined with positron emission tomography
Objective: To investigate the cause of chronic neuroleptic drug-induced parkinsonism (NIP) through examination of the profile of striatal monoaminergic nerve terminal density using positron emission…Dopaminergic denervation in de-novo Parkinson’s disease. Does functional somatotopy plays a role?
Objective: To clarify how dopaminergic denervation occurs along the dorsoventral axis of the posterior putamen in the earliest stages of PD. Background: Dopamine loss in…Topographical subtypes of multiple system atrophy: MRI and PET studies
Objective: To investigate the MSA subtypes based on the topography of MSA lesions, employing MRI, PET with [18F]FP-CIT and [18F]FDG PET. Background: Based on the…
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