Muscarinic M2 cholinergic receptors in cervical dystonia
Objective: To characterize the M2 muscarinic acetylcholine receptor binding in patients with cervical dystonia, measured with non-invasive high-resolution PET, using [18F]FP-TZTP ligand. Background: While antimuscarinic…Retinal thickness as a marker of disease progression in progressive supranuclear palsy
Objective: We measured changes of retinal thickness, and compare them with clinical features and intracranial neurodegeneration in progressive supranuclear palsy (PSP) cohort. Background: PSP has a…White matter structural network of motor reserve in early Parkinson’s disease
Objective: This study aims to explore the white matter structural network associated with motor reserve (i.e., individual capacity to cope with nigrostriatal dopamine depletion) in…Diagnostic value of striatal [18F]-FP-DTBZ PET in Parkinson’s disease
Objective: To detect the difference of dopaminergic integrity between PDs and healthy controls (HC) using [18F]-FP-DTBZ PET in vivo and to obtain the diagnostic value…Synaptic density in cortical and subcortical gray matter is associated with mild parkinsonian signs (MPS) in healthy older adults: a [11C] UCB-J PET study
Objective: to investigate if a reduction in cortical and subcortical synaptic density measured in vivo with the synaptic vesicle protein 2A (SV2A) binding [11C] UCB-J…Brain glia activation and peripheral inflammation in Parkinson’s disease: a PET study
Objective: Abnormal activation of immune system is an important pathogenesis of Parkinson's disease, but the relationship between peripheral inflammation, central glia activation and dopaminergic degeneration…GPi-DBS induced brain metabolic activation in cervical dystonia
Objective: To investigate the effects of GPi-DBS on brain glucose metabolism locally at the stimulation site and across the whole brain in patients with cervical…Short-latency afferent inhibition for the assessment of cholinergic degeneration in Parkinson’s disease
Objective: Our objective is to assess how well short-latency afferent inhibition (SAI) represents cortical cholinergic system integrity in patients with Parkinson’s disease (PD), using cholinergic…Activity and sleep associated with changes in glymphatic imaging-markers in Parkinson Disease patients enrolled in 3-month exercise program
Objective: To investigate whether intensity of activity and quality of sleep during a 3-month exercise program for patients with Parkinson Disease (PD) are associated with…Patterns of early-phase 18F-FP-CIT PET images and the risk of dementia conversion in Parkinson’s disease
Objective: This study aims to investigate the prognostic relevance of the patterns of early-phase 18F-fluorinated N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane (18F-FP-CIT) positron emission tomography (PET) images in patients…
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