Language impairment in Corticobasal Syndrome: from clinical phenotype to biomarkers
Objective: To investigate the language impairment profile of patients diagnosed as probable Corticobasal Syndrome (CBS) [1] in light of a multimodal imaging biomarkers analysis, namely…Lateralized Tau Pathology in a Case of Lewy Body Dementia with Corticobasal Syndrome
Objective: To measure bilateral in vivo and postmortem tau pathology in a well-characterized patient presenting with corticobasal syndrome (CBS) due to underlying neocortical stage Lewy…Cognitive reserve in non-demented patients with Parkinson’s disease might protect against amyloid burden effect on cognition
Objective: To evaluate the effect of cognitive reserve (CR) in patients with Parkinson’s disease (PD) without dementia. Background: CR concept is a principal factor explaining…Striatal dopaminergic loss in early clinically unilateral Parkinson’s disease: a systematic review
Objective: To quantify the extent of dopaminergic loss in early clinically unilateral PD from studies using presynaptic dopamine imaging with either single photon emission computed tomography…Insulin resistance and Parkinson’s disease
Objective: To investigate peripheral insulin resistance and cerebral FDG-PET changes in Parkinson’s disease (PD). Background: Glycated hemoglobin levels (HbA1c) is used as a marker of…Clinical correlates of Parkinson’s disease metabolic pattern: not only a diagnostic tool
Objective: To define and cross-validate the glucose metabolism abnormalities related to Parkinson's Disease (PD), and to analyze pattern relationship with clinical phenotype Background: In PD,…Characteristics of the amyloid beta networks in Parkinson’s disease patients: a PPMI study
Objective: The impact that amyloid beta (Aβ) accumulation in the brain has on the progression of Parkinson’s disease (PD) pathology is complex and poorly understood…Dissociated longitudinal evolution of limbic serotonergic and striatal dopaminergic and serotonergic pathology in apathetic and non-apathetic patients in early Parkinson’s disease
Objective: To investigate the longitudinal changes in striatal and extra-striatal dopaminergic and serotonergic innervation in apathetic and non-apathetic patients during the five years after the…Cognition-related functional topographies in Parkinson’s disease: Localized loss of the ventral default mode network
Objective: We sought to determine whether functional network abnormalities seen in patients with Parkinson’s disease (PD) and cognitive decline reflect the loss of the default…Significant hypometabolism in the posterior parietal cortex and precuneus in Parkinson’s disease with GBA mutations: [18F]FDG PET study
Objective: We explored [18F]FDG PET findings of PD patients with GBA mutation. Background: Parkinson’s disease (PD) with glucocerebrosidase (GBA) mutations is characterized by early onset…
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