Brain 5-HT1 receptor binding in multiple system atrophy: A [18F]-MPPF PET study
Objective: The primary objective was to compare brain 5-HT1a receptor binding between patients with multiple system atrophy (MSA) and healthy controls (HC). The secondary objectives…A longitudinal PET study to assess the state of microglia activation in a Phase 2 study of Laquinimod as a treatment for Huntington’s disease (LEGATO-HD)
Objective: To assess in vivo in Huntington’s disease (HD) changes in microglia activation state, due to treatment with laquinimod, as reflected by changes in 11C-PBR28…Distinct compensatory and maladaptive wiring patterns in genotypic Parkinson’s disease
Objective: Although disease networks have been identified in Parkinson’s disease (PD) using functional imaging, it is unclear whether these represent maladaptive or compensatory responses to…Clinical profile and cerebral metabolic characteristic of cognitive impairments in multiple system atrophy
Objective: This study aimed to characterize the cognitive profiles of multiple system atrophy (MSA) and explore the possible mechanisms involved using 18F-fluorodeoxyglucose (FDG) Positron Emission…The usefulness of a dual-phase 18-F-FP-CIT PET in a case of Alzheimer’s disease with slow movement
Objective: To think about the usefulness of a dual-phase 18-F-FP-CIT PET in cases of dementia with bradykinesia. Background: A classic 18-F-FP-CIT PET is useful in…FDG PET and MIBG scintigraphy in the differential diagnosis of parkinsonism: a head-to-head comparison
Objective: To compare the performance of [18F]fluorodeoxyglucose (FDG) PET and [123I]metaiodobenzylguanidine (MIBG) scintigraphy in the differential diagnosis of parkinsonism in the same patient sample. Background:…18kDa Translocator Protein PET in 4-Repeat Tauopathies – A Cross-Sectional Single Center Study
Objective: The aim of this single center study was to analyse the potential of 18F-GE-180 TSPO PET as a biomarker in 4R-tauopathies. Background: The pathological…Abnormal pattern of brain glucose metabolism in multiple system atrophy
Objective: To define and cross-validate the brain glucose metabolic abnormalities in patients with a clinical diagnosis of Multiple System Atrophy (MSA). Background: Despite the availability…Identifying neural signatures of Parkinson’s disease that predict decline in gait and postural control
Objective: To identify Parkinson’s disease [PD] specific patterns in the brain using a multi-modal neuroimaging design and use these to predict gait decline. Background: Gait…FDG-PET degeneration patterns predict amyloid deposition in Corticobasal Syndrome
Objective: To investigate if an individual clinically-focused analysis of brain FDG-PET metabolic patterns and a comprehensive neurological evaluation could distinguish Corticobasal Syndrome (CBS) pathological variants…
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