IPSC-derived Cortical Neurons from Parkinson’s Patients with VPS35 Mutation show Defects in Synapto- and Neurogenesis
Objective: Investigate whether the Parkinson’s disease (PD) VPS35 D620N mutation leads to synaptic dysfunction in human cortical iPSC-derived neurons. Background: Early presynaptic dysfunction and cortico-striatal…Enviromental Risk Factors for Parkinson’s Disease in the Nigeria Parkinson’s Disease Research Network
Objective: To determine the risk factors associated with Parkinson’s disease (PD) development in the Nigerian PD Research (NPDR) cohort Background: PD is widely believed to…Effect of Diabetes Mellitus on the Phenotype of Parkinson’s Disease
Objective: In this study, we aim to investigate whether Type 2 diabetes (T2DM) influences the phenotype of Parkinson’s disease (PD). Background: In PD, T2DM may…EMPOWER-PD: Testing and evaluation of an 8-week co-created Self-management program tailored People with Parkinson`s disease and their caregivers in an interventional follow-up study
Objective: This study aims to test a 8-week self-management program, developed collaboratively with People with PD (PwP), caregivers, healthcare professionals and other stakeholders using a…Increasing access to Deep Brain Stimulation for an underserved patient population: A retrospective cohort from an urban hospital in a diverse county in the USA.
Objective: To understand whether the presence of a Bilingual Movement Disorder specialist increases access to Deep Brain Stimulation (DBS) for an underserved patient population. Background:…Impact of Prior Head Trauma on Parkinson’s Disease Experience
Objective: We aim to characterize the impact of prior head trauma on Parkinson’s disease (PD) related outcomes. Background: Previous head trauma is correlated with detrimental…Exploring Vestibulopathy in PD: Distinguishing PD from Age-related Presbyvestibulopathy via Dynamic Gait and Balance Assessment
Objective: To investigate the influence of age-associated vestibulopathy (presbyvestibulopathy, PVP) on dynamic gait and balance in Parkinson's disease (PD) patients and elderly controls. We hypothesized…Real-world use of biomarkers for Parkinsonism: Should I do this (pSyn) or DaT?
Objective: To examine the utility of commercially available skin phosphorylated alpha-synuclein deposition test (pSyn) in patients with clinically ambiguous parkinsonism and its concordance with dopamine…Comparison of Composite Method Calculations for Monitoring Disease Progression in Early Parkinson’s Disease
Objective: Objective: To evaluate the influence of composite scoring methodologies using digital measures of gait, tremor, and bradykinesia to monitor disease progression over one year…Subthalamic Nucleus Stimulation Modulates Cognitive Theory of Mind in Parkinson’s Disease
Objective: This study aims to investigate the effect of subthalamic nucleus (STN) deep brain stimulation (DBS) on ToM using the Parkinson’s disease (PD) model. Background:…
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