Levodopa response in pathology-confirmed Parkinson’s Disease, Multiple System Atrophy and Progressive Supranuclear Palsy
Objective: to describe the rate of levodopa response, phenotypical characteristics, prognostic implications and pathological features in a large cohort of patients with pathology-confirmed Parkinson’s disease…The Impact of Freezing of Gait on Falls over time in Parkinson’s disease
Objective: To quantify falls related to Freezing of Gait (FoG) versus unrelated to FoG as Parkinson’s disease progresses. Background: FoG is a debilitating symptom of…Evaluation of Effects of Levodopa and Subthalamic Nucleus Stimulation (STN-DBS) on Gait using Quantified Timed Up and Go Test in People with Parkinson’s Disease (PD)
Objective: This study evaluates effect of medication and stimulation on transfers and gait in people with PD post STN-DBS using an automated, quantitative assessment involving…Parkinson’s Disease Diagnosed in a Patient with Anti-Musk Positive Myasthenia Gravis: Coincidence? – Case Report and Literature Review
Objective: To describe a case of a male patient presenting with anti-Musk positive Myasthenia Gravis (MG) and Parkinson's Disease (PD) with an adequate response to…A Registry for Sleep and Circadian Health Quality in Parkinson’s Disease (ReSCQu-PD)
Objective: To characterize sleep-, circadian- and disease-related factors contributing to daytime sleepiness in a cohort of people with Parkinson’s Disease (PwPD). Background: Excessive daytime sleepiness…PINK1 activation improves outcomes in the UQCRC1 models of Parkinson’s disease
Objective: To investigate the role of chronic oxidative phosphorylation (OXPHOS) stress in mitophagy and the therapeutic potential of PINK1 activation in the UQCRC1 models of…Profiling Neural Protein Dopaminylation in Parkinson’s disease
Objective: The hallmark of Parkinson’s Disease is motor dysfunction from the decline in dopaminergic cells in the substantia nigra (SN), leading to the development of…Effect of Aβ on α-synuclein propagation
Objective: To investigate how amyloid-beta (Aβ) pathology affects α-synuclein (α-syn) propagation. Background: Lewy bodies, the pathological hallmark of Parkinson’s disease and dementia with Lewy bodies,…Prevalence and Clinical Characteristics of iNPH-Related Imaging Findings (DESH) in Parkinson’s Disease
Objective: To investigate the prevalence of idiopathic normal pressure hydrocephalus (iNPH)-related imaging findings (DESH) and their clinical characteristics in Parkinson’s disease (PD) patients. Background: PD…MultiModal Transformer-Based Detection of Parkinson’s Disease in fMRI Extracted Time Series
Objective: Develop and evaluate a multimodal, transformer-based pipeline for detecting Parkinson’s disease (PD) from resting-state fMRI time series, aiming to expose short-lived neural connectivity disruptions…
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