Tumeric and Curcumin Improve Motor Function and Reduce Catalepsy in a Rotenone -Induced Parkinson’s Disease Model
Objective: Catalepsy measurements play a crucial role in behavioral research on Parkinson’s disease (PD), as they reflect significant motor impairments associated with dopaminergic dysfunction. In…Enhancing Sleep in Parkinson’s Disease: A Retrospective Study on Group CBT-I
Objective: Weill Cornell Sleep Center and our movement disorder team developed a treatment program for individuals with Parkinson’s Disease (PD) with sleep disturbances. The goal…Relationships Between Preferred Walking Speed and Accelerations at the Head and Trunk in Individuals with Parkinson’s Disease (PD) and Healthy Elderly
Objective: To assess the relationship between head and trunk accelerations and the preferred walking speed (PWS) in individuals with and without PD Background: Bradykinesia and…Prospective observational study on the effects of physical exercise and lifestyle modifications in patients with Parkinson’s disease
Objective: This study aimed to assess the effectiveness of physical activity, which includes all movements that increase energy expenditure, in conjunction with exercise, characterized as…Clinicians’ Views on the Use of a Patient Decision Aid for DBS in Parkinson’s Disease
Objective: To assess neurologists’ awareness of, and experience using, patient decision aids. Background: Patients with Parkinson’s disease (PD), their caregivers, and medical teams encounter numerous…Longitudinal Analysis of BRAIN test in isolated REM sleep behaviour disorder with and without hyposmia.
Objective: To assess motor dysfunction in individuals with polysomnography (PSG)-confirmed isolated REM Sleep Behaviour Disorder (iRBD), self-reported RBD (sRBD), and sRBD with smell loss (hyposmia).…Pharmacokinetic Analysis of Subcutaneous Levodopa/Carbidopa Delivery With ND0612
Objective: To (i) use a population pharmacokinetic (PK) model to compare predicted levodopa PK parameters when levodopa is delivered as investigational ND0612, as oral immediate-release…Risk of Motor Complications in Early Parkinson’s Disease Patients Treated with Opicapone in the EPSILON study: Effect of Levodopa Dose
Objective: This post-hoc analysis of the EPSILON study evaluated whether levodopa dose (<400mg/day vs. ≥400mg/day) and opicapone (OPC) timing (at double-blind [DB] or open-label extension…Continuous Subcutaneous Apomorphine Infusion (CSAI) Reduces OFF Periods and Extends Periods of GOOD ON Time: Heatmap Analysis of the TOLEDO Study
Objective: Use heatmap analysis to quantify and examine diurnal patterns of OFF and GOOD ON time periods throughout the day, and changes in the number…Efficacy of ND0612 in Patients at Different Stages of Disease Severity: Subgroup-Analyses From a Randomized, Active-Controlled Study in People With Parkinson’s Disease Experiencing Motor Fluctuations
Objective: To evaluate the efficacy of investigational ND0612 in reducing motor fluctuations in patients with Parkinson’s disease (PD) at different stages of disease and/or symptom…
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