Quality of Life with 24-hour Subcutaneous Levodopa/Carbidopa Infusion (ND0612): PDQ-39 Results from a Phase 3 Randomized Active-Controlled Study
Objective: Evaluate quality of life (QoL) data from the Phase 3 randomized, active-controlled BouNDless study. Background: Pivotal data from the BouNDless study (NCT04006210) showed that…Gait Digital Outcomes Exploration from Continuous Real-World Recordings in Parkinson’s Disease
Objective: To measure how people with Parkinson's disease (PD) feel, function, and survive, derived from continuous recordings with a wearable ankle inertial device in a real-world…Efficacy of Continuous Subcutaneous Levodopa/Carbidopa Infusion (ND0612) on Motor Signs of PD and Experiences of Daily Living
Objective: Evaluate the effect of investigational ND0612 on motor signs of PD and motor experiences of daily living (m-EDL), as assessed using the MDS-UPDRS. Background:…GRoningen Early-PD Ambroxol Treatment (GREAT) Trial: A randomized, double-blind, placebo-controlled, single center trial with ambroxol in Parkinson patients with a GBA-mutation
Objective: To study the potential disease-modifying properties of ambroxol in PD patients with a GBA1 mutation Background: The most common genetic risk factor for Parkinson’s…A Pilot Study of Intrajejunal Faecal Microbiota Transplant to Improve Motor Function in Patients with Parkinson’s Disease Treated with Levodopa-carbidopa Intestinal Gel: Preliminary Findings.
Objective: To determine whether faecal microbiota transplant (FMT) improves motor function in patients with Parkinson Disease (PD) treated with levodopa/carbidopa intestinal gel (LCIG). Background: Preliminary…Long-Term Evolution of Advanced Parkinson’s Disease Burden: Subgroup Analysis from the 24 Month International PROSPECT Observational Study
Objective: To evaluate the long-term evolution of clinical outcomes and treatment patterns in people with advanced Parkinson’s disease (PwaPD) whose symptoms are inadequately controlled by…Analgesic effect of electroacupuncture on Relieving pain in Parkinson’s disease and the mechanism based on rs-fMRI
Objective: To investigate whether electroacupuncture (EA) on the primary motor cortex could reduce pain in patients with PD and to explore the mechanism behind its…Design, synthesis and pharmacological evaluation of 16-pyridylmethylene derivatives of steroidal oximes as antiparkinsonian agents in MPTP-injected mice.
Objective: The objective of the present study is focused on the design and synthesis of 16-pyridyl methylene derivatives of steroidal oximes and further their pharmacological…The impact of multimodal forms of art therapy on treatment outcomes and quality of life in Parkinson’s disease
Objective: Assessing the impact of art therapy on treatment outcomes and quality of life in Parkinson's disease (PD). Background: In addition to medical treatment, art…Clinical benefit of Opicapone in patients with different Parkinson disease phenopytes. The OPTIMO study
Objective: To assess the clinical benefit induced by opicapone (OPC) as an add-on therapy to levodopa in fluctuating Parkinson’s disease (PD) patients with special focus…
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