Determining and Leveraging Local Ancestry to Assess Individual-Level Risk: from the Global Parkinson’s Genetics Program
Objective: We develop a scalable pipeline leveraging existing tools to determine local ancestry for all individuals in the Global Parkinson’s Genetics Program (GP2), aiming to…Understanding diffusion in extracellular space in synucleinopathy
Objective: To understand the extracellular space (ECS) diffusion in synucleinopathy. Background: The pathogenic mechanisms underlying synucleinopathies involve the spread and propagation of α-synuclein aggregates throughout…Levels of change in interleukin-6 levels according to clinical stages of Parkinson’s disease in patients with and without Covid-19
Objective: Comparison of serum IL-6 levels in clinical stages Parkinson's disease patients with and without Сovid-19. Background: Elevated levels of the cytokine IL-6 may indicate…Age-associated Changes in Microglial Morphology and its Role in Deciphering Susceptibility to Parkinson’s Disease
Objective: To delineate the age-associated changes in microglial morphotypes in the substantia nigra pars compacta (SNpc) of C57BL/6J and CD-1 mice and alterations in response…Neuropeptide Alterations in Parkinson’s Disease: A Meta-Analysis
Objective: To analyze the levels of different neuropeptides in patients with Parkinson’s disease (PD) compared to healthy individuals. Background: Neuropeptides are bioactive molecules that play…Can Square Wave Jerks Differentiate Progressive Supranuclear Palsy from Parkinson’s Disease? A Scoping Review
Objective: To review the available literature regarding the presence and properties of square wave jerks (SWJs) in Progressive Supranuclear Palsy (PSP) and Parkinson’s Disease (PD).…Benefits of Parkinson’s Team Training Are Maintained Long-Term
Objective: To determine if the improvements in confidence to provide and coordinate patient care and understanding of individual and other team member roles among interprofessional…Patient-reported changes from normal in individuals with prodromal and early-motor Parkinson’s disease: a scoping review
Objective: To synthesize published literature about patient-reported symptoms (PRS) or changes from normal in prodromal and early motor stages of Parkinson’s disease (PD) and develop…Association between use of Furosemide and Risk of Parkinson’s disease
Objective: Main objective of study is to check the association between furosemide use and risk of Parkinson's disease (PD) in a Finnish nationwide nested case-control…MDS Clinical Supportive Criteria for Parkinson’s Disease are Associated with α-Synuclein Seed Amplification Assay Status
Objective: To assess the association between α-synuclein seed amplification assay (α-synuclein SAA) status with the supportive criteria of the MDS Clinical Diagnostic Criteria for Parkinson’s…
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