Global Momentum in Parkinson’s Disease Therapeutics: Ten-Year Trends in Mechanisms, Modalities, and Clinical Endpoints
Objective: To characterize current trends in Parkinson’s disease (PD) clinical development by analyzing global interventional trials from the past decade, focusing on trial phase distribution,…Unveiling Oculomotor Phenotypes in Parkinson’s Disease: A Multidimensional Clustering Analysis
Objective: To characterize distinct Parkinson’s Disease (PD) oculomotor phenotypes and evaluate their correlation with motor severity, cognitive function, and non-motor symptom (NMS) profiles using unsupervised…Early-Onset and Familial Parkinson’s Disease in Kyrgyzstan: A PD Cohort Subset for Family-Based Genetic Studies
Objective: To characterize early-onset and familial PD cases within a Kyrgyz PD cohort and assess their potential for future family-based genetic studies. Background: Early-onset PD…Impact of Multi-day Wearable Monitoring on Neurologists’ Assessment of Motor Fluctuations and Treatment Strategies in Parkinson’s Disease: A Real-World Study
Objective: To assess the impact of wearable-device objective metrics on neurologists’ perception and therapeutic decisions in a real-world cohort of patients with Parkinson’s disease (PD).…Improving Community Access to Parkinson’s Disease Clinical Trials: Protocol for a Regional Navigation Toolkit in Southern California
Objective: To develop and pilot a regional Clinical Trials Navigation Toolkit to improve community neurologist awareness of Parkinson’s disease (PD) clinical trials and support equitable…Toward Global Best Practices for Managing Skin Complications in Subcutaneous Infusion Therapy for Parkinson’s Disease: A Nursing and Advanced Practice Perspective
Objective: The International Parkinson’s Disease Nurse and Advanced Practice Study Group within the International Parkinson’s and Movement Disorder Society conducted this survey to identify current…The Impact of Dopamine-Induced Impulse Control Disorders on Quality of Life in Young-Onset Parkinson’s Disease
Objective: To quantify how impulse control disorders (ICDs) alter day-to-day functionality and overall quality of life (QoL) among individuals living with Young-Onset Parkinson’s Disease (YOPD),…Comparison Of Levodopa Dose Frequency And Parkinson’s Kinetigraph Metrics For Screening Advanced Parkinson’s Disease
Objective: 1. Evaluate how well levodopa dose frequency and Parkinson's Kinetigraph (PKG) metrics correspond with the 5-2-1 criteria for identifying Advanced Parkinson Disease (APD)2. Determine…Determinant factor of tremor recurrence after Vim-FUS in ET and tremor-dominant PD
Objective: To identify clinical and technical predictors of recurrence of tremor in our own cohort of ET and TDPD patients undergoing Vim-FUS Background: Vim-FUS improves…Micro- and Nanoplastics in Parkinson’s Disease Pathogenesis An Emerging Environmental Risk Factor
Objective: To synthesize current experimental and translational evidence supporting the hypothesis that micro- and nanoplastics (MNPs) may contribute to Parkinson’s disease (PD) pathogenesis through neuroinflammatory…
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