Secular trends and survival of Parkinson’s disease and other forms of parkinsonism in the United Kingdom
Objective: We examined the UK incidence, prevalence and survival for eight parkinsonian disorders including Parkinson’s disease (PD) from 2003 to 2023, using primary and secondary…The Complexity of Neuropsychiatric Symptoms Assessment in Parkinson’s Disease: A Rasch Analysis of the Mild Behavioral Impairment-Checklist
Objective: This study aims to evaluate the psychometric properties of the Mild Behavioral Impairment-Checklist (MBI-C) in Parkinson’s Disease (PD) using Rasch measurement theory. Background: The…The Impact of Metabolic Syndrome on Parkinson’s Disease Progression: A Systematic Review
Objective: We aimed to identify the impact of Metabolic syndrome (MS) in motor and non-motor symptoms of Parkinson's disease (PD). Background: PD is a common…Decline in Motor Function and Cognitive Abilities in GBA PD Compared to Idiopathic PD (iPD)
Objective: To compare disease progression events between GBA PD and iPD using the Parkinson’s Progression Markers Initiative (PPMI) database Background: GBA PD patients exhibit more…Apathy and Risk of Parkinson’s Disease: A Population-Based Cohort Study
Objective: This study investigated the association between apathy and the risk of incident Parkinson's disease (PD) in community-dwelling adults. Background: Apathy is a core neuropsychiatric…Complement C4 Exacerbates Inflammation and Neuronal Damage in Vivo
Objective: To investigate the specific effects of the core complement component C4 on α-synuclein aggregation and neuroinflammation during the pathogenesis of PD. Background: Synucleinopathies are…χ-DBS: An Open-Source Susceptibility Atlas Tool for Deep Brain Stimulation Target Visualization and Segmentation
Objective: This work is motivated by the need for atlas creation tools for susceptibility maps presurgically acquired for deep brain stimulation (DBS). Segmentations aid in…Differentiating Parkinsonism and related diseases by specific Parkinsonism patterns
Objective: This study aimed to identify characteristic parkinsonism patterns across PD, MSA and PSP, and evaluate their utility in early differentiation. Background: Parkinson's disease (PD), multiple…Dopamine Transporter Imaging as a Predictor of Functional Outcomes in Parkinson’s Disease
Objective: To evaluate the prognostic value of dopamine transporter (DAT) imaging in predicting future disability, as well as motor and non-motor burden, in Parkinson’s disease…Dual task elicited premotor and supplementary motor activity as sensitive markers of mild Parkinson’s disease: an fNIRS analysis
Objective: This study aimed to explore dual-task (DT)-related cortical hemodynamic response (CHR) differences across healthy older adults (HOA), mild Parkinson’s disease (PD), and moderate PD…
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