Antipsychotic Prescriptions Among Nursing Home Residents with Parkinson’s Disease in the End-of-Life Period
Objective: To determine whether antipsychotic prescriptions differ between community-dwelling and nursing home residents with PD in the last 6 months of life. Background: Most antipsychotics…Deciphering the Role of Auranofin-Loaded Nanoparticles Against Rotenone Model of Parkinson’s Disease: Via GSK-3β/ Nrf2/HO-1 Signaling Pathways
Objective: To investigate the neuroprotective effect of AUF-loaded nanoparticles in animal models of Parkinson's disease by modulating GSK-3β/ Nrf2/HO-1 Signaling Pathways. Background: Parkinson's disease (PD) is…Genetic signatures stratify PwP into three subgroups with differing responses in two disease-modifying Phase 3 trials and indicate multiple disease biology pathways to Parkinson’s Disease
Objective: To evaluate if 3 newfound genetic subgroups represent differing aspects of disease biology in PD by determining if subgroup participants have differing responses to…Safety and Tolerability of Bemdaneprocel in People With Parkinson’s Disease: Results up to 24 Months From a Phase 1 Study
Objective: To report the safety and tolerability of bemdaneprocel in participants with Parkinson’s disease (PD) up to 24 months post transplantation. Background: Bemdaneprocel is an…Quantification of Neuroinflammation and White Matter Injury in Parkinson Disease Using Diffusion Basis Spectrum Imaging
Objective: To investigate differences in white matter (WM) using Diffusion Basis Spectrum Imaging (DBSI) between participants with Parkinson’s disease (PD) and controls and to examine…Cerebrovascular Reactivity and Glymphatic Clearance in Parkinson’s disease
Objective: To evaluate whether altered cerebrovascular reactivity contributes to reduced glymphatic clearance in Parkinson’s disease (PD). Background: Cerebrovascular activity is a major factor driving cerebrospinal…The 2-Minute Walking Test Predicts Aerobic Fitness, Motor Function, and Brain Health in Parkinson’s Disease
Objective: To determine the association of performance on the 2-Minute Walking Test (2MWT) with aerobic fitness, motor and cognitive function, and brain health in mild…Transcranial Sonography of the Substantia Nigra and Vagus Nerve Ultrasonography as Complementary Diagnosis for Parkinson’s Disease.
Objective: We aim to investigate the relationship between sonographic abnormalities of the substantia nigra, vagus nerve cross-sectional area and clinical features of PD in different…Safety and effectiveness of staged bilateral MR-guided focused ultrasound pallidothalamic tractotomy for motor complications of Parkinson’s disease: study protocol
Objective: To describe the protocol of a study evaluating the safety and effectiveness of magnetic resonance-guided focused ultrasound (MRgFUS) pallidothalamic tractotomy (PTT) as a staged…Subthalamic Local Field Potential Monitoring in Parkinson’s Disease during Epidural Electric Spinal Cord Stimulation
Objective: Investigate STN local field potential (LFP) changes in a patient with PD during spinal cord stimulation (SCS). Background: SCS is explored as a possible…
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