iPLA2β controls ER-mitochondria tethering and Ca2+ transfer in Parkinson’s disease
Objective: In this study, we aimed to investigate whether Parkinson's disease (PD) associated calcium-independent phospholipase A2β (iPLA2β) regulates the integrity and functions of endoplasmic reticulum…Transcriptomic and Proteomic Profiling for Effective Deep Brain Stimulation in Parkinson’s Disease
Objective: To determine whether transcriptomic and proteomic changes predict better motor outcomes after deep brain stimulation (DBS) surgery in Parkinson’s disease (PD). Background: DBS is…Developing a Supervised Machine Learning Model for Long-Term Cognitive Status Prediction in Parkinson Disease
Objective: The study aims to develop a supervised machine learning (ML) model to predict long-term cognitive outcome in patients with Parkinson disease (PD). Background: Cognitive…A Kinematic and fMRI Study of the Neural Correlates of Bradykinesia in Parkinson’s Disease
Objective: This study aimed at investigating the neural and kinematic correlates of bradykinesia during hand-tapping in people with Parkinson’s disease (pwPD) relative to healthy controls.…MRI Predictive Marker of the Vestibular Galvanic Stimulation Effectiveness in the Postural Instability Treatment in Parkinson’s Disease.
Objective: To assess the galvanic vestibular stimulation (GVS) effect on axial symptoms and cervical vestibular evoked myogenic potential (cVEMP) depending on the Magnetic Resonance Parkinsonism…Longitudinal Structural and Functional Correlates of Progression in Isolated Rapid Eye Movement Sleep Behaviour Disorder
Objective: To identify progressive structural and functional imaging alterations in a longitudinal cohort of patients with isolated rapid eye movement sleep behavior disorder (iRBD). Background:…Mapping Cholinergic Signaling in Parkinson Disease Using [18F]VAT
Objective: To determine how cholinergic signaling changes within Parkinson Disease (PD) and how these differences relate to the progression of cognitive and behavioral symptoms. Background:…Perceptions Regarding Asleep and Awake DBS Among Neurologists and Neurosurgeons
Objective: To compare trends and perceptions regarding Asleep and Awake deep brain stimulation (DBS) between neurologists (NLGs) and neurosurgeons (NSXs) in the USA and abroad.…Real-world Experiences of Image-guided Programming in Subthalamic Nucleus Deep Brain Stimulation in Parkinson’s disease
Objective: We evaluated the effectiveness of image-guided programming (IGP) in patients with Parkinson’s disease (PD) who underwent bilateral subthalamic nucleus (STN) – deep brain stimulation…Functional connectivity enhances prediction of STN DBS motor outcomes
Objective: To assess the predictive value of functional and volumetric MRI data in comparison to clinical data alone for STN DBS outcomes. Background: While STN…
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