Latent Genetic Architecture of Parkinson’s Disease Risk factors and Comorbidities
Objective: To comprehensively investigate the genetic relationship between Parkinson’s disease (PD), its risk factors, and comorbidities by constructing a factor model of the shared genetic…A UK-wide Effort for Identification of Loci for Autosomal Dominant Parkinson’s Disease
Objective: (i) To describe the demographic, clinical and genetic features of a large cohort of familial autosomal dominant Parkinson’s disease (PD) patients in the UK.(ii)…Real-Time Removal of Stimulus Artifact for Closed-Loop Deep Brain Stimulation by Synchronized Sample-And-Hold Artifact Blanking (SSAB): Verification in Animal Model
Objective: To develop and validate a real-time stimulus artifact removal analog front-end (AFE) by synchronized sample-and-hold artifact blanking (SSAB) technique with the Parkinsonian minipig model…Linear Mixed-Effect Modelling of Antisaccades in Parkinson’s Disease and Progressive Supranuclear Palsy
Objective: This study aims to investigate variations in antisaccade parameters (latency, damping ratio, peak velocity, and amplitude) among different stages of Parkinson's Disease (PD), Progressive…IPSC-derived Cortical Neurons from Parkinson’s Patients with VPS35 Mutation show Defects in Synapto- and Neurogenesis
Objective: Investigate whether the Parkinson’s disease (PD) VPS35 D620N mutation leads to synaptic dysfunction in human cortical iPSC-derived neurons. Background: Early presynaptic dysfunction and cortico-striatal…Enviromental Risk Factors for Parkinson’s Disease in the Nigeria Parkinson’s Disease Research Network
Objective: To determine the risk factors associated with Parkinson’s disease (PD) development in the Nigerian PD Research (NPDR) cohort Background: PD is widely believed to…Effect of Diabetes Mellitus on the Phenotype of Parkinson’s Disease
Objective: In this study, we aim to investigate whether Type 2 diabetes (T2DM) influences the phenotype of Parkinson’s disease (PD). Background: In PD, T2DM may…EMPOWER-PD: Testing and evaluation of an 8-week co-created Self-management program tailored People with Parkinson`s disease and their caregivers in an interventional follow-up study
Objective: This study aims to test a 8-week self-management program, developed collaboratively with People with PD (PwP), caregivers, healthcare professionals and other stakeholders using a…Increasing access to Deep Brain Stimulation for an underserved patient population: A retrospective cohort from an urban hospital in a diverse county in the USA.
Objective: To understand whether the presence of a Bilingual Movement Disorder specialist increases access to Deep Brain Stimulation (DBS) for an underserved patient population. Background:…Impact of Prior Head Trauma on Parkinson’s Disease Experience
Objective: We aim to characterize the impact of prior head trauma on Parkinson’s disease (PD) related outcomes. Background: Previous head trauma is correlated with detrimental…
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