Data-driven identification of distinct fronto-subcortical and cortical-posterior subtypes of cognitive decline in Parkinson’s disease
Objective: To use a novel data-driven approach, Subtype and Stage inference (SuStain)[1], for identifying distinct subtypes of domain-specific cognitive decline in Parkinson’s disease (PD), and…Cortico-cortical connectivity is normalised by levodopa in tremor-dominant Parkinson’s disease
Objective: The aim of this study was to examine whether connectivity between the supplementary motor area and primary motor cortex (SMA-M1) is implicated in Parkinson’s…Intraoperative quantification of MDS-UPDRS tremor measurements using 3D accelerometry
Objective: This study focuses on translating parkinsonian tremor tests to an objective method to rate tremor severity using 3D accelerometry, that can be used during…Monitoring disease course by sensor-based gait analysis: gait symmetry and motor impairment progression in Parkinson’s disease.
Objective: Evaluate gait symmetry index as progression marker for motor impairment in patients with Parkinson’s disease (PD). Background: PD is a neurodegenerative disease characterized by…The association of CSF sTREM2 with cognitive decline and its dynamic change in Parkinson’s disease: Analysis of the PPMI Cohort
Objective: This study aims to investigate the baseline and longitudinal changes of soluble fragments of triggering receptor expressed on myeloid cells 2 (sTREM2) in cerebrospinal…Detection and Analysis of Spatio-Temporal Variables of Parkinsonian Gait Using PODOSmart® Insoles
Objective: Objective: Typical Parkinsonian gait detection and analysis is heavily dependent on expensive sensors and human labor. Here we propose the use of PODOSmart® insoles,…sleep disturbance and wakefulness in parkinson’s disease
Objective: a complete study of sleep disorders and their adequate treatment Background: Sleep and wake disturbances are the second most common non-motor symptom of Parkinson's…Manifestations of Parkinson’s Disease in different ethnicities in Sumatera Indonesia: A Descriptive Study
Objective: To describe manifestations of Parkinson’s Disease (PD) in different ethnicities in Sumatera, Indonesia. Background: Prevalence of PD is varied around the world. Some studies…Visual system abnormalities and visual hallucinations in Parkinson’s disease
Objective: We aimed to identify clinical and imaging biomarkers of visual system injury associated with the presence of Visual hallucinations (VH) in Parkinson's disease (PD).…Alterations in neuron-derived exosomal cargo in Parkinson Disease
Objective: The main objectives are 1) the confirmation of exosome isolation, based on iPSC-derived midbrain neuron model, 2) the identification of α-synuclein cargo of PD-patient…
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