Cinpanemab in Parkinson’s Disease: Imaging and Fluid Biomarker Results from the Phase 2 SPARK Study
Objective: To evaluate the effects of cinpanemab on biomarkers in participants with Parkinson’s disease (PD). Background: SPARK (NCT03318523) was designed to evaluate the safety, pharmacokinetics,…The Hauser Diary knowledge test as a tool to improve Rater Training Programs in Parkinson’s disease clinical trials
Objective: To identify the areas with specific training needs for Rater Training Programs (RTP) on the Hauser Diary in Parkinson’s disease (PD) clinical trials Background:…Secondary endpoints of a randomized, placebo-Controlled Pilot Study to evaluate the safety of lyophilized PRIM-DJ2727 in Parkinson’s disease
Objective: To evaluate the impact of fecal microbiome transplant (FMT) on disease progression as a secondary outcome of a safety study using PRIM-DJ2727 in Parkinson's…The EON (Elderly patients on ONgentys) study in Parkinson’s disease: design and rationale of a prospective non-interventional trial
Objective: To assess the tolerability of opicapone (OPC) when used in elderly patients with Parkinson’s disease (PD) in real-world conditions. Background: OPC proved to be…Opicapone Analysis of Health Economic Costs in Clinical Practice in Parkinson’s Disease UK Patients with Motor Fluctuations: Findings from the OPTIPARK Study
Objective: To assess the influence of a 6-month treatment with opicapone (OPC) on the costs for the care of Parkinson’s disease (PD) patients. Background: OPC…Levodopa/carbidopa intestinal gel (LCIG) reduces fluctuations and shortens time to on without troublesome dyskinesia in advanced Parkinson’s Disease: Post-hoc analyses of 54-week LCIG-monotherapy trial
Objective: To assess the long-term effectiveness of LCIG monotherapy on reducing daily health-state fluctuations and time to on without troublesome dyskinesia (ONwoTD) after waking Background:…The gender gap in Parkinson’s disease before and after Subthalamic Nucleus Deep Brain Stimulation surgery: preliminary results of a retrospective study.
Objective: Gender differences in several neurodegenerative disorders have been extensively investigated. Nowadays, evidence and interest about sex-related distinctions regarding Parkinson's disease (PD) are increasing. The aim…SARS CoV2 in older patients with Parkinson’s.
Objective: To review the clinical presentation and management of SARS-CoV 2 in older patients with Parkinson’s during the first wave of the pandemic in West…Physical activity and subjective perception of PD symptoms during COVID-19 lockdown: a clinical audit
Objective: To establish the effects of COVID-19 “lockdown” on physical activity and patients' perception of PD symptoms. Background: Physical activity in Parkinson Disease (PD) is…Informant vs. Self-ratings of Activities of Daily Living in Parkinson’s Disease patients
Objective: To compare patient and informant ratings of impairments in activities of daily living (ADL) of Parkinson’s Disease (PD) patients. Background: Valid ratings of ADL…